ReviewRevista panamericana de salud publica = Pan American journal of public health2018
Economic impact of dengue fever in Latin America and the Caribbean: a systematic review.
Review in Revista panamericana de salud publica = Pan American journal of public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Cost of dengue in Colombia: A systematic review.PLoS neglected tropical diseases · 2024Pooled it
- Article
- Epidemiological Characteristics of Dengue Disease in Mexico (2014-2025): A Descriptive Analysis of a Hyperendemic Country.Pathogens (Basel, Switzerland) · 2026Review
- Engineered Nanobodies for early and accurate diagnosis of dengue virus infection.PLoS neglected tropical diseases · 2025Article
- No time to wait: resilience as a cornerstone for primary health care across Latin America and the Caribbean, a World Bank-PAHO Lancet Regional Health Americas Commission.Lancet regional health. Americas · 2025Review
- Chemical Composition and Larvicidal Activity AgainstMolecules (Basel, Switzerland) · 2025Article
- Rio Mamore Hantavirus Endemicity, Peruvian Amazon, 2020.Emerging infectious diseases · 2024Article
- The Dynamic Relationship between Dengue Virus and the Human Cutaneous Innate Immune Response.Viruses · 2024Review
- Dengue.Lancet (London, England) · 2024Review
- Sustainable Dengue Prevention and Management: Integrating Dengue Vaccination Strategies with Population Perspectives.Vaccines · 2024Article
- Natural vertical transmission of dengue virus in Latin America and the Caribbean: highlighting its detection limitations and potential significance.Parasites & vectors · 2023Review
- Viremia and Inflammatory Cytokines in Dengue: Interleukin-2 as a Biomarker of Infection, and Interferon-α and -γ as Markers of Primary versus Secondary Infection.Pathogens (Basel, Switzerland) · 2023Article
- Direct and indirect effects of age on dengue severity: The mediating role of secondary infection.PLoS neglected tropical diseases · 2023Article
- Prevention of a dengue outbreak via the large-scale deployment of Sterile Insect Technology in a Brazilian city: a prospective study.Lancet regional health. Americas · 2023Article
- Dengue as a Disease Threatening Global Health: A Narrative Review Focusing on Latin America and Brazil.Tropical medicine and infectious disease · 2023Review
- Importance ofBiosafety and health · 2023Review
- Article
- Prevalence of arboviruses and other infectious causes of skin rash in patients treated at a tertiary health unit in the Brazilian Amazon.PLoS neglected tropical diseases · 2022Article
- Dengue outbreak in the times of COVID-19 pandemic: Common myths associated with the dengue.Annals of medicine and surgery (2012) · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess the economic impact of dengue in Latin America and the Caribbean using a systematic review that includes studies not previously considered by other reviews.
methodsCochrane methodology was used to conduct a systematic review of the cost of dengue in Latin America. PubMed Central, EMBASE, and the Biblioteca Virtual en Salud-which includes scientific, peer-reviewed journals not indexed by other databases-were searched from inception through August 2016. All articles that reported cost of illness data for countries in Latin America were included. Included studies underwent a methodological appraisal using a seven-question instrument designed for cost of illness studies. Extracted data were direct and indirect costs for outpatient and hospitalized cases and total cost of the disease. Values were adjusted to 2015 US dollars using the consumer price index.
resultsFrom a total of 848 initial references, 17 studies were included, mainly from Brazil, Colombia, Cuba, Mexico, and Puerto Rico; costs were available for 39 countries. The methodological appraisal showed that 70% of the studies met more than 70% of the evaluated items. The main economic impact of dengue was due to productivity costs. Average annual cost was more than US$ 3 billion. Direct costs represented over 70% of the total share for hospitalized cases. For outpatients, direct medical costs were low, but social costs were significant since indirect costs may account for up to 80% of the total cost.
conclusionsDengue fever has a significant economic impact in Latin America. It is essential to develop new public health interventions, such as dengue vaccination, to decrease the propagation of the disease and its total cost.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.