Evidence map›Paper›PMID 31093027›Full record

ReviewContrast media & molecular imaging2019

Renal Allograft Rejection: Noninvasive Ultrasound- and MRI-Based Diagnostics.

Ulrich Jehn, Katharina Schuette-Nuetgen, Dominik Kentrup, Verena Hoerr, Stefan Reuter

Abstract readReview
In one paragraph

Review in Contrast media & molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. [Therapeutic response and monitoring of antibody-mediated renal graft rejection].Revista medica del Instituto Mexicano del Seguro Social · 2025
    Article
  5. Article
  6. Article
  7. Thermal Rejection Assessment: New Strategies for Early Detection.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ulrich JehnDepartment of Medicine, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Muenster, 48149 Münster, Germany.ORCID 0000-0003-1136-438X
Katharina Schuette-NuetgenDepartment of Medicine, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Muenster, 48149 Münster, Germany.
Dominik KentrupDepartment of Medicine, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Muenster, 48149 Münster, Germany.
Verena HoerrDepartment of Clinical Radiology, University Hospital of Muenster, 48149 Münster, Germany.
Stefan ReuterDepartment of Medicine, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Muenster, 48149 Münster, Germany.ORCID 0000-0002-3011-8347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, allogeneic kidney transplantation remains the best available therapeutic option for patients with end-stage renal disease regarding overall survival and quality of life. Despite the advancements in immunosuppressive drugs and protocols, episodes of acute allograft rejection, a sterile inflammatory process, continue to endanger allograft survival. Since effective treatment for acute rejection episodes is available, instant diagnosis of this potentially reversible graft injury is imperative. Although histological examination by invasive core needle biopsy of the graft remains the gold standard for the diagnosis of ongoing rejection, it is always associated with the risk of causing substantial graft injury as a result of the biopsy procedure itself. At the same time, biopsies are not immediately feasible for a considerable number of patients taking anticoagulants due to the high risk of complications such as bleeding and uneven distribution of pathological changes within the graft. This can result in the wrong diagnosis due to the small size of the tissue sample taken. Therefore, there is a need for a tool that overcomes these problems by being noninvasive and capable of assessing the whole organ at the same time for specific and fast detection of acute allograft rejection. In this article, we review current state-of-the-art approaches for noninvasive diagnostics of acute renal transplant inflammation, i.e., rejection. We especially focus on nonradiation-based methods using magnetic resonance imaging (MRI) and ultrasound.

Indexed as

Magnetic Resonance ImagingUltrasonographyGraft RejectionHumansKidneyKidney TransplantationTransplantation, Homologous

Identifiers

PMID31093027
PMCPMC6481101

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.