Evidence map›Paper›PMID 31092925›Full record

ArticleNature2019

Progenitors from the central nervous system drive neurogenesis in cancer.

Philippe Mauffrey, Nicolas Tchitchek, Vilma Barroca, Alexis-Pierre Bemelmans, Virginie Firlej, Yves Allory, Paul-Henri Roméo, Claire Magnon

Erratum issuedOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 202 papers.

0numbers the graph read from it
0cells of the map it votes in
202citing papers in PubMed
27.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

202 citing papers in PubMed, 333 citations in OpenAlex.

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142 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Philippe MauffreyUMR967 (Laboratoire Cancer et Microenvironnement ATIP/AVENIR-INSERM-CEA), Institut de Radiobiologie Cellulaire et Moléculaire, Institut de Biologie François Jacob, Direction de la Recherche Fondamentale, Paris, France.
Nicolas Tchitchek *UMR1184 (INSERM-CEA-Université Paris Saclay), Infectious Diseases Models for Innovative Therapies, Institut de Biologie François Jacob, Direction de la Recherche Fondamentale, Paris, France.
Vilma Barroca *UMR967 (Laboratoire Cancer et Microenvironnement ATIP/AVENIR-INSERM-CEA), Institut de Radiobiologie Cellulaire et Moléculaire, Institut de Biologie François Jacob, Direction de la Recherche Fondamentale, Paris, France.
Alexis-Pierre BemelmansUMR9199 (CNRS-CEA-Université Paris-Saclay), Molecular Imaging Research CENter, Institut de Biologie François Jacob, Direction de la Recherche Fondamentale, Paris, France.
Virginie FirlejU955 (INSERM), Hôpital Henri Mondor-Université Paris-Est, Paris, France.
Yves AlloryDepartment of Pathology, Institut Curie, Paris, France.
Paul-Henri RoméoUMR967 (INSERM-CEA-Université Paris Diderot-Université Paris Saclay), Laboratoire Réparation et Transcription dans les Cellules Souches, Institut de Radiobiologie Cellulaire et Moléculaire, Institut de Biologie François Jacob, Direction de la Recherche Fondamentale, Paris, France.
Claire MagnonUMR967 (Laboratoire Cancer et Microenvironnement ATIP/AVENIR-INSERM-CEA), Institut de Radiobiologie Cellulaire et Moléculaire, Institut de Biologie François Jacob, Direction de la Recherche Fondamentale, Paris, France. claire.magnon@cea.fr.
Inserm · FRCentre National de la Recherche Scientifique · FRHôpital Foch · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autonomic nerve fibres in the tumour microenvironment regulate cancer initiation and dissemination, but how nerves emerge in tumours is currently unknown. Here we show that neural progenitors from the central nervous system that express doublecortin (DCX

Indexed as

NeurogenesisAdenocarcinomaAdrenergic NeuronsAnimalsCarcinogenesisCell DifferentiationCentral Nervous SystemDisease Models, AnimalDoublecortin Domain ProteinsDoublecortin ProteinGenes, mycHumansLateral VentriclesMaleMiceMicrotubule-Associated ProteinsDCX protein, humanDcx protein, mouseDoublecortin Domain ProteinsDoublecortin ProteinMicrotubule-Associated ProteinsNeuropeptides

Identifiers

PMID31092925
OpenAlexW2945293993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.