Evidence map›Paper›PMID 31092908›Full record

ReviewBritish journal of cancer2019

Lipid metabolism in cancer cells under metabolic stress.

Rimsha Munir, Jan Lisec, Johannes V Swinnen, Nousheen Zaidi

Open access · hybridAbstract readReview
In one paragraph

Review in British journal of cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 234 papers.

0numbers the graph read from it
0cells of the map it votes in
234citing papers in PubMed
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

234 citing papers in PubMed, 367 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
  5. Article
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  7. Article
  8. Lipidomic profile of meningiomas harboring different NF2 mutation status.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Lipid Metabolism and Oncogenesis.Cancer treatment and research · 2026
    Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review

174 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Rimsha MunirCancer Biology Lab, MMG, University of the Punjab, Lahore, 54590, Pakistan.
Jan LisecBundesanstalt für Materialforschung und -prüfung (BAM), Department of Analytical Chemistry, Richard-Willstätter-Straße 11, 12489, Berlin, Germany.
Johannes V SwinnenLaboratory of Lipid Metabolism and Cancer, Department of Oncology, Faculty of Medicine, KU Leuven, Leuven, Belgium.
Nousheen ZaidiCancer Biology Lab, MMG, University of the Punjab, Lahore, 54590, Pakistan. nousheen-zehra.zaldl@charite.de.
University of the Punjab · PKFederal Institute For Materials Research and Testing · DEKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer cells are often exposed to a metabolically challenging environment with scarce availability of oxygen and nutrients. This metabolic stress leads to changes in the balance between the endogenous synthesis and exogenous uptake of fatty acids, which are needed by cells for membrane biogenesis, energy production and protein modification. Alterations in lipid metabolism and, consequently, lipid composition have important therapeutic implications, as they affect the survival, membrane dynamics and therapy response of cancer cells. In this article, we provide an overview of recent insights into the regulation of lipid metabolism in cancer cells under metabolic stress and discuss how this metabolic adaptation helps cancer cells thrive in a harsh tumour microenvironment.

Indexed as

Cell HypoxiaFatty Acid SynthasesHumansLipid MetabolismNeoplasmsNutrientsOxygenStress, PhysiologicalFatty Acid SynthasesNutrientsOxygen

Identifiers

PMID31092908
PMCPMC6738079
OpenAlexW2945059856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.