ArticleScientific reports2019
Peripheral blood lymphocyte subsets change after steroid withdrawal in renal allograft recipients: a prospective study.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Effect of panel reactive antibodies on T cell immunity reinstatement following renal transplantation.World journal of transplantation · 2022Article
- Article
- Changes in T and B cell subsets in end stage renal disease patients before and after kidney transplantation.Immunity & ageing : I & A · 2021Article
- Long-Term Redistribution of Peripheral Lymphocyte Subpopulations after Switching from Calcineurin to mTOR Inhibitors in Kidney Transplant Recipients.Journal of clinical medicine · 2020Article
- A cluster of differentiation 19 + B-lymphocyte cell as a predictor of relapse in pemphigus vulgaris.Indian journal of dermatology, venereology and leprologyArticle
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several studies have assessed clinical outcomes after steroid withdrawal (SW) in kidney transplant (KT) recipients, but little is known about its potential impact on lymphocyte subpopulations. We designed a prospective study to evaluate the long-term impact of SW in 19 KT recipients compared to 16 KT recipients without changes in immunosuppression (steroid maintenance, SM). We assessed renal function, presence of HLA antibodies and peripheral blood lymphocyte subsets at time of inclusion, and 3, 12 and 24 months later. The immunophenotype of 20 healthy subjects was also analyzed. Serum creatinine and proteinuria remained stable in SW and SM patients. SW did not associate with generation of de novo donor-specific antibodies. SW patients showed decreases in T-lymphocytes (p < 0.001), and in the CD4
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