Evidence map›Paper›PMID 31092815›Full record

ArticleNature communications2019

Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis.

Margery Cortes-Clerget, Nnamdi Akporji, Jianguang Zhou, Feng Gao, Pengfei Guo, Michael Parmentier, Fabrice Gallou, Jean-Yves Berthon, Bruce H Lipshutz

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 233 citations in OpenAlex.

  1. Review
  2. Nanomaterial Integration at Liquid-Liquid Interfaces for Green Catalysis.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Is Micellar Catalysis Green Chemistry?Molecules (Basel, Switzerland) · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Margery Cortes-ClergetDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA, 93106, USA.ORCID http://orcid.org/0000-0002-8358-1925
Nnamdi AkporjiDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA, 93106, USA.
Jianguang ZhouChemical and Analytical Development, Suzhou Novartis Pharma Technology Company Limited, 215537, Changshu, Jiangsu, China.
Feng GaoChemical and Analytical Development, Suzhou Novartis Pharma Technology Company Limited, 215537, Changshu, Jiangsu, China.
Pengfei GuoChemical and Analytical Development, Suzhou Novartis Pharma Technology Company Limited, 215537, Changshu, Jiangsu, China.
Michael ParmentierChemical & Analytical Development, Novartis Pharma AG, 4056, Basel, Switzerland.
Fabrice GallouChemical & Analytical Development, Novartis Pharma AG, 4056, Basel, Switzerland.ORCID http://orcid.org/0000-0001-8996-6079
Jean-Yves BerthonGREENTECH, Biopôle Clermont Limagne, 63360, St Beauzire, France.
Bruce H LipshutzDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA, 93106, USA. bhlipshutz@ucsb.edu.
Novartis (China) · CNUniversity of California, Santa Barbara · USNovartis (Switzerland) · CHGreentech (France) · FR

Funding

Upgrade of 500 MHz NMR SpectrometerS10OD012077 · OD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI ZHANG, LIMING · 2013 to 2013
$347k
NIH HHS S10 OD012077
6 · The paper itself

Abstract

Previous studies have shown that aqueous solutions of designer surfactants enable a wide variety of valuable transformations in synthetic organic chemistry. Since reactions take place within the inner hydrophobic cores of these tailor-made nanoreactors, and products made therein are in dynamic exchange between micelles through the water, opportunities exist to use enzymes to effect secondary processes. Herein we report that ketone-containing products, formed via initial transition metal-catalyzed reactions based on Pd, Cu, Rh, Fe and Au, can be followed in the same pot by enzymatic reductions mediated by alcohol dehydrogenases. Most noteworthy is the finding that nanomicelles present in the water appear to function not only as a medium for both chemo- and bio-catalysis, but as a reservoir for substrates, products, and catalysts, decreasing noncompetitive enzyme inhibition.

Indexed as

CatalysisChemistry, OrganicEnzymesMetalsMicellesMolecular StructureSurface-Active AgentsTransition ElementsWaterEnzymesMetalsMicellesSurface-Active AgentsTransition ElementsWater

Identifiers

PMID31092815
PMCPMC6520378
OpenAlexW2946012049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.