ArticleThe Biochemical journal2019
Tissue-specific characterization of mitochondrial branched-chain keto acid oxidation using a multiplexed assay platform.
Article in The Biochemical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Short-changed: Limited short-chain fatty acid oxidative capacity in skeletal muscle mitochondria.The Journal of physiology · 2026Article
- Exercise training induces mitochondrial biogenesis, while high-fat diet increases the ability of mitochondria to use long and short-chain fatty acids.The Journal of physiology · 2026Article
- Branched-chain amino acids and their metabolites decrease human and rat hepatic stellate cell activation.Molecular biology reports · 2024Article
- Article
- Medium-chain fatty acid oxidation is independent of l-carnitine in liver and kidney but not in heart and skeletal muscle.American journal of physiology. Gastrointestinal and liver physiology · 2023Article
- Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction.Nature metabolism · 2023Review
- Skeletal muscle undergoes fiber type metabolic switch without myosin heavy chain switch in response to defective fatty acid oxidation.Molecular metabolism · 2022Article
- Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart.Nature communications · 2021Article
- Transporters at the Interface between Cytosolic and Mitochondrial Amino Acid Metabolism.Metabolites · 2021Review
- Octanoate is differentially metabolized in liver and muscle and fails to rescue cardiomyopathy in CPT2 deficiency.Journal of lipid research · 2021Article
- Revisiting Mitochondrial Bioenergetics: Experimental Considerations for Biological Interpretation.Function (Oxford, England) · 2021Article
- Preference and detrimental effects of high fat, sugar, and salt diet in wild-caught Drosophila simulans are reversed by flight exercise.FASEB bioAdvances · 2021Article
- Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure.The Journal of biological chemistry · 2020Article
- Branched-chain ketoacid overload inhibits insulin action in the muscle.The Journal of biological chemistry · 2020Article
- Novel approach to quantify mitochondrial content and intrinsic bioenergetic efficiency across organs.Scientific reports · 2020Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
15 authors.
Funding
Abstract
Alterations to branched-chain keto acid (BCKA) oxidation have been implicated in a wide variety of human diseases, ranging from diabetes to cancer. Although global shifts in BCKA metabolism-evident by gene transcription, metabolite profiling, and
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.