ArticleJournal of clinical microbiology2019
Detailed Analysis of the Characteristics of Sample Volume in Blood Culture Bottles.
Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- In-depth analysis of sampling practice and yield of blood cultures.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Observational
- Quantitative association of blood culture volume with contaminant and pathogen recovery.Infectious medicine · 2026Article
- Diagnostic value of blood culture growth patterns in distinguishing contaminants from pathogens.Journal of clinical microbiology · 2026Article
- Quality improvement project to improve blood culture volumes in haematology patients.BMJ open quality · 2026Article
- Enhancing blood culture volume with ultrathin-wall cannula devices.Journal of clinical microbiology · 2025Article
- Detection of relevant pathogens and contaminants in blood cultures after implementation of single-sampling strategy and initial specimen diversion.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- Bloodstream Infection and Associated Factors at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, 2023: A Prospective Cross-Sectional Study.BioMed research international · 2025Article
- Microbiological performance and adherence in blood culture protocols: The role of a second anaerobic bottle.Heliyon · 2024Article
- Deficits in blood culture collection in the emergency department if sepsis is suspected: results of a retrospective cohort study.Infection · 2024Article
- Intermittent hemodialysis: a review of the top antimicrobial stewardship practices to be employed.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024Review
- Subculturing and Gram staining of blood cultures flagged negative by the BACTEC™ FX system: Optimizing the workflow for detection ofFrontiers in microbiology · 2023Article
- Factors impacting the pre-analytical quality of blood cultures-Analysis at a tertiary medical center.PloS one · 2023Article
- Using a 29-mRNA Host Response Classifier To Detect Bacterial Coinfections and Predict Outcomes in COVID-19 Patients Presenting to the Emergency Department.Microbiology spectrum · 2022Article
- Unresolved issues in the epidemiology and diagnosis of bacteremia: an opinion paper.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022Review
- Diagnosis of Bloodstream Infections: An Evolution of Technologies towards Accurate and Rapid Identification and Antibiotic Susceptibility Testing.Antibiotics (Basel, Switzerland) · 2022Review
- Detection of bacterial co-infections and prediction of fatal outcomes in COVID-19 patients presenting to the emergency department using a 29 mRNA host response classifier.medRxiv : the preprint server for health sciences · 2022Article
- Blood Culture Utilization in the Hospital Setting: a Call for Diagnostic Stewardship.Journal of clinical microbiology · 2022Review
- Single-Site Sampling versus Multisite Sampling for Blood Cultures: a Retrospective Clinical Study.Journal of clinical microbiology · 2022Article
- Effects of Blood Culture Aerobic/Anaerobic Bottle Collection Patterns from Both Sides of the Body on Positive Blood Culture Rate and Time-to-Positivity.Infection and drug resistance · 2022Article
- The diagnostic value of next-generation sequencing technology in sepsis.Frontiers in cellular and infection microbiology · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blood volume is the most important variable for the detection of microorganisms in blood cultures (BCs). Most standards recommend 40 to 60 ml blood, collected in several BC bottles filled up to 10 ml. We measured blood volume in individual BC bottles and analyzed the associations of hospital, bottle type, day of the week, daily sampling time, and age and sex of the patient with sampling volume and BC result. The variation in blood volume per BC bottle was analyzed in a mixed linear model using hospital, bottle type, weekday, sampling time, age, and sex as fixed factors and patient identification (ID) and episode as random factors to control for repetitive sampling of individual patients. Only 18% of all bottles were filled with the recommended 8 to 10 ml, and 47% were filled with less than 8 ml. The mean (± standard error) volume was larger in positive bottles (9.09 ± 0.15) than in negative bottles (8.47 ± 0.07) (
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