Evidence map›Paper›PMID 31092556›Full record

ArticleThe Journal of cell biology2019

Proteome of the central apparatus of a ciliary axoneme.

Lei Zhao, Yuqing Hou, Tyler Picariello, Branch Craige, George B Witman

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
  2. Comparative Proteomics of Plasma and Flagellar Membranes inInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Heterogeneity of radial spoke components in Tetrahymena cilia.Cellular and molecular life sciences : CMLS · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The methylome of motile cilia.Molecular biology of the cell · 2024
    Article
  14. Review
  15. Article
  16. Concurrent loss of ciliary genesRoyal Society open science · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lei ZhaoDivision of Cell Biology and Imaging, Department of Radiology, University of Massachusetts Medical School, Worcester, MA.
Yuqing HouDivision of Cell Biology and Imaging, Department of Radiology, University of Massachusetts Medical School, Worcester, MA.ORCID 0000-0002-7038-675X
Tyler PicarielloDivision of Cell Biology and Imaging, Department of Radiology, University of Massachusetts Medical School, Worcester, MA.ORCID 0000-0003-0049-1148
Branch CraigeDivision of Cell Biology and Imaging, Department of Radiology, University of Massachusetts Medical School, Worcester, MA.ORCID 0000-0003-3180-5947
George B WitmanDivision of Cell Biology and Imaging, Department of Radiology, University of Massachusetts Medical School, Worcester, MA george.witman@umassmed.edu.ORCID 0000-0002-9497-9218
University of Massachusetts Chan Medical School · US

Funding

Flagellar Motility and AssemlbyR37GM030626 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI WITMAN, GEORGE B · 2007 to 2016
$6.3M
Flagellar Motility and AssemblyR35GM122574 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI WITMAN, GEORGE B · 2017 to 2021
$3.1M
NIGMS NIH HHS R35 GM122574NIGMS NIH HHS R37 GM030626
6 · The paper itself

Abstract

Nearly all motile cilia have a "9+2" axoneme containing a central apparatus (CA), consisting of two central microtubules with projections, that is essential for motility. To date, only 22 proteins are known to be CA components. To identify new candidate CA proteins, we used mass spectrometry to compare axonemes of wild-type

Indexed as

Algal ProteinsAxonemeCell MovementChlamydomonasCiliaFlagellaMass SpectrometryMicrotubule ProteinsMutationProteomeAlgal ProteinsMicrotubule ProteinsProteome

Identifiers

PMID31092556
PMCPMC6548120
OpenAlexW2945153995

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.