Evidence map›Paper›PMID 31092503›Full record

ArticleDevelopment (Cambridge, England)2019

Functional analysis of Niemann-Pick disease type C family protein, NPC1a, in

Tzofia Bialistoky, Diane Manry, Peyton Smith, Christopher Ng, Yunah Kim, Sol Zamir, Victoria Moyal, Rachel Kalifa, Paul Schedl, Offer Gerlitz and 1 more

Open access · greenAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Hedgehog and Drosophila germ cell migration.Development (Cambridge, England) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Tzofia BialistokyDevelopmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Diane ManryDepartment of Molecular Biology, Princeton University, Princeton, NJ 08540, USA.
Peyton SmithDepartment of Molecular Biology, Princeton University, Princeton, NJ 08540, USA.
Christopher NgDepartment of Molecular Biology, Princeton University, Princeton, NJ 08540, USA.
Yunah KimDepartment of Molecular Biology, Princeton University, Princeton, NJ 08540, USA.
Sol ZamirDevelopmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Victoria MoyalDevelopmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Rachel KalifaDevelopmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Paul SchedlDepartment of Molecular Biology, Princeton University, Princeton, NJ 08540, USA.
Offer GerlitzDevelopmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem, Israel gdeshpan@princeton.edu offerg@ekmd.huji.ac.il.ORCID 0000-0002-1574-2088
Girish DeshpandeDepartment of Molecular Biology, Princeton University, Princeton, NJ 08540, USA gdeshpan@princeton.edu offerg@ekmd.huji.ac.il.ORCID 0000-0002-2426-7872
Princeton University · US

Funding

Involvement of calcium channels in directed germ cell migrationR21HD093913 · NICHD · PRINCETON UNIVERSITY · PI SCHEDL, PAUL D · 2018 to 2019
$446k
NICHD NIH HHS R21 HD093913
6 · The paper itself

Abstract

During embryonic gonad coalescence, primordial germ cells (PGCs) follow a carefully choreographed migratory route circumscribed by guidance signals towards somatic gonadal precursor cells (SGPs). In

Indexed as

AnimalsCell MovementDrosophila melanogasterDrosophila ProteinsGene Expression Regulation, DevelopmentalGerm CellsHeterozygoteMembrane ProteinsNeuronsNiemann-Pick C1 ProteinSignal TransductionDrosophila ProteinsMembrane ProteinsNiemann-Pick C1 ProteinNpc1a protein, DrosophilaCell migrationDrosophila melanogasterEmbryogenesisPrimordial germ cells

Identifiers

PMID31092503
PMCPMC6550021
OpenAlexW2946423734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.