Evidence map›Paper›PMID 31092294›Full record

ReviewClinical epigenetics2019

Functional roles of lncRNAs and its potential mechanisms in neuropathic pain.

Simin Tang, Jun Zhou, Huan Jing, Meijuan Liao, Sen Lin, Zhenxing Huang, Teng Huang, Jiying Zhong, HanbingWang

Open access · goldAbstract readReview
In one paragraph

Review in Clinical epigenetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. The Downregulation of Opioid Receptors and Neuropathic Pain.International journal of molecular sciences · 2023
    Review
  5. Review
  6. Ion channel long non-coding RNAs in neuropathic pain.Pflugers Archiv : European journal of physiology · 2022
    Review
  7. miRNA-22 UpregulatesOxidative medicine and cellular longevity · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The Emerging Role of lncRNAs in Spinal Cord Injury.BioMed research international · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Simin TangDepartment of Anesthesiology, The First People's Hospital of Foshan, Foshan, 528000, Guangdong Province, China.
Jun ZhouDepartment of Anesthesiology, The First People's Hospital of Foshan, Foshan, 528000, Guangdong Province, China. zhoujun7843@126.com.
Huan JingDepartment of Anesthesiology, The First People's Hospital of Foshan, Foshan, 528000, Guangdong Province, China.
Meijuan LiaoDepartment of Anesthesiology, The First People's Hospital of Foshan, Foshan, 528000, Guangdong Province, China.
Sen LinDepartment of Anesthesiology, The First People's Hospital of Foshan, Foshan, 528000, Guangdong Province, China.
Zhenxing HuangDepartment of Anesthesiology, The First People's Hospital of Foshan, Foshan, 528000, Guangdong Province, China.
Teng HuangDepartment of Anesthesiology, The First People's Hospital of Foshan, Foshan, 528000, Guangdong Province, China.
Jiying ZhongDepartment of Anesthesiology, The First People's Hospital of Foshan, Foshan, 528000, Guangdong Province, China.
HanbingWangDepartment of Anesthesiology, The First People's Hospital of Foshan, Foshan, 528000, Guangdong Province, China.
First People's Hospital of Foshan · CNZunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuropathic pain (NP) is ranked as one of the major forms of chronic pain and emerges as a direct consequence of a lesion or disease affecting the somatosensory nervous system. Despite great advances into the mechanisms of NP, clinical practice is still not satisfactory. Fortunately, progress in elucidating unique features and multiple molecular mechanisms of long non-coding RNAs (lncRNAs) in NP has emerged in the past 10 years, suggesting that novel therapeutic strategies for pain treatment may be proposed. In this review, we will concentrate on recent studies associated with lncRNAs in NP. First, we will describe the alterations of lncRNA expression after spinal cord injury (SCI) and peripheral nerve injury (PNI), and then we illustrate the role of some specific lncRNAs in detail, which may offer new insights into our understanding of the etiology and pathophysiology of NP. Finally, we put special emphasis on the altered expression of lncRNAs in the diverse biological process of NP. Recent advances we summarized above in the development of NP may facilitate translation of these findings from bench to bedside in the future.

Indexed as

DNA MethylationEpigenesis, GeneticGene Expression RegulationHumansNeuralgiaRNA, Long NoncodingRNA, Long NoncodingCentral nerve injurylncRNAsNeuropathic painPeripheral nerve injurySpinal cord injury

Identifiers

PMID31092294
PMCPMC6521530
OpenAlexW2948020460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.