Evidence map›Paper›PMID 31092218›Full record

SynthesisBMC public health2019

Prevalence of dementia in the People's Republic of China from 1985 to 2015: a systematic review and meta-regression analysis.

Yangjun Zhu, Hao Liu, Xi-Li Lu, Bo Zhang, Wanwen Weng, Jun Yang, Jun Zhang, Meng-Jie Dong

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  10. Tauopathies: new perspectives and challenges.Molecular neurodegeneration · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yangjun ZhuDepartment of Ultrasound, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, People's Republic of China.
Hao LiuThe Department of Nuclear Medicine, the First Affiliated Hospital, College of Medicine, Zhejiang University, 79 QingChun Road, Hangzhou, 310003, People's Republic of China.
Xi-Li LuThe Department of Nuclear Medicine, the First Affiliated Hospital, College of Medicine, Zhejiang University, 79 QingChun Road, Hangzhou, 310003, People's Republic of China.
Bo ZhangThe Department of Nuclear Medicine, the First Affiliated Hospital, College of Medicine, Zhejiang University, 79 QingChun Road, Hangzhou, 310003, People's Republic of China.
Wanwen WengThe Department of Nuclear Medicine, the First Affiliated Hospital, College of Medicine, Zhejiang University, 79 QingChun Road, Hangzhou, 310003, People's Republic of China.
Jun YangThe Department of Nuclear Medicine, the First Affiliated Hospital, College of Medicine, Zhejiang University, 79 QingChun Road, Hangzhou, 310003, People's Republic of China.
Jun ZhangThe Department of Nuclear Medicine, the First Affiliated Hospital, College of Medicine, Zhejiang University, 79 QingChun Road, Hangzhou, 310003, People's Republic of China.
Meng-Jie DongThe Department of Nuclear Medicine, the First Affiliated Hospital, College of Medicine, Zhejiang University, 79 QingChun Road, Hangzhou, 310003, People's Republic of China. dmjlzf2016@zju.edu.cn.ORCID http://orcid.org/0000-0002-1306-1959

Funding

Medical and Health Science and Technology Project of Zhejiang Province 2015KYB153National Natural Science Foundation of China 81471704Zhejiang Provincial Natural Science Foundation of China LY15H180007
6 · The paper itself

Abstract

backgroundIn China, the most populous developing country in the world, dementia represents a serious challenge. We performed a large-scale systematic review and meta-regression analysis to elucidate the prevalence of dementia and its subtypes and to identify potential factors underlying the differences between articles.

methodsA comprehensive literature search was conducted in the following databases to identify studies published up to December 2015: Cochrane Library, CBMDISK, Chongqing VIP, CNKI, PubMed and EMBASE. All statistical analyses (including subtype and meta-regression analyses) were performed with R version 3.3.3.

resultsIn total, 51 surveys were selected. The pooled prevalence rates of dementia and its main subtypes, namely, Alzheimer's disease (AD) and vascular dementia (VAD), for the population aged 55 years and older were 4.03, 2.44 and 1.09%, respectively. The outcomes showed that the meta-regression analysis was affected by the publication year, sample size, region and diagnostic criteria.

conclusionsOur analysis provided reliable estimates of the prevalence of dementia/ AD/ VD over the past 30 years, which may be affected by education level, and diagnostic criteria. The prevalence of AD/VAD was higher in northern than in southern China, which warrants further study.

Indexed as

AgedAlzheimer DiseaseChinaDatabases, FactualDementiaDementia, VascularHumansMiddle AgedPrevalenceRegression AnalysisAlzheimer’s diseaseChinaDementiaPrevalenceVascular dementia

Identifiers

PMID31092218
PMCPMC6521412

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.