Evidence map›Paper›PMID 31091977›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Low availability of choline

Isis Trujillo-Gonzalez, Walter B Friday, Carolyn A Munson, Amelia Bachleda, Ellen R Weiss, Nazia M Alam, Wei Sha, Steven H Zeisel, Natalia Surzenko

Open access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. External Disruption of Ocular DevelopmentThe Yale journal of biology and medicine · 2024
    Review
  7. Biallelic variation in the choline and ethanolamine transportermedRxiv : the preprint server for health sciences · 2024
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Role of Choline in Ocular Diseases.International journal of molecular sciences · 2021
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Isis Trujillo-GonzalezNutrition Research Institute, University of North Carolina-Chapel Hill, Kannapolis, North Carolina, USA.
Walter B FridayNutrition Research Institute, University of North Carolina-Chapel Hill, Kannapolis, North Carolina, USA.
Carolyn A MunsonNutrition Research Institute, University of North Carolina-Chapel Hill, Kannapolis, North Carolina, USA.
Amelia BachledaDepartment of Cell Biology and Physiology, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA.
Ellen R WeissDepartment of Cell Biology and Physiology, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA.
Nazia M AlamDepartment of Physiology and Biophysics, Weill Cornell Medical College, New York, New York, USA.
Wei ShaBioinformatics Services Division, University of North Carolina-Charlotte, Kannapolis, North Carolina, USA.
Steven H ZeiselNutrition Research Institute, University of North Carolina-Chapel Hill, Kannapolis, North Carolina, USA.
Natalia SurzenkoNutrition Research Institute, University of North Carolina-Chapel Hill, Kannapolis, North Carolina, USA.
David H. Murdock Research Institute · USUniversity of North Carolina at Chapel Hill · USBurke Medical Research Institute · USUniversity of North Carolina at Charlotte · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David Darr · 1985 to 2026
$201.5M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian Michael Carroll · 1999 to 2026
$31.6M
Nutrigenetic analysis of choline status biomarkersR01DK115380 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZEISEL, STEVEN H · 2018 to 2021
$2.8M
NCI NIH HHS P30 CA016086NIDDK NIH HHS P30 DK056350NIDDK NIH HHS R01 DK115380NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

Adequate supply of choline, an essential nutrient, is necessary to support proper brain development. Whether prenatal choline availability plays a role in development of the visual system is currently unknown. In this study, we addressed the role of

Indexed as

AnimalsCell CycleCell DifferentiationCholineCholine DeficiencyDietDown-RegulationFemaleMiceMice, Inbred C57BLMice, TransgenicNeurofibromin 2NeurogenesisPregnancyRetinaRetinal Cone Photoreceptor CellsCholineNeurofibromin 2maternal nutritionNf2/Merlinretinal developmentvisual sensitivity

Identifiers

PMID31091977
PMCPMC6662989
OpenAlexW2946519292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.