Evidence map›Paper›PMID 31091795›Full record

ArticleCancers2019

Acidification is an Essential Process of Cold Atmospheric Plasma and Promotes the Anti-Cancer Effect on Malignant Melanoma Cells.

Christin Schneider, Lisa Gebhardt, Stephanie Arndt, Sigrid Karrer, Julia L Zimmermann, Michael J M Fischer, Anja-Katrin Bosserhoff

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  6. Review
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  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. The Role of Calcium Signaling in Melanoma.International journal of molecular sciences · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Christin SchneiderInstitute of Biochemistry, Emil-Fischer-Center, University of Erlangen-Nürnberg, 91054 Erlangen, Germany. christin.schneider@fau.de.
Lisa GebhardtInstitute of Physiology and Pathophysiology, University of Erlangen-Nürnberg, 91054 Erlangen, Germany. lisa.gebhardt@fau.de.
Stephanie ArndtDepartment of Dermatology, University Hospital Regensburg, 93053 Regensburg, Germany. stephanie.arndt@ukr.de.
Sigrid KarrerDepartment of Dermatology, University Hospital Regensburg, 93053 Regensburg, Germany. sigrid.karrer@ukr.de.
Julia L ZimmermannTerraplasma medical GmbH, 85748 Garching, Germany. zimmermann@terraplasm.com.
Michael J M FischerInstitute of Physiology and Pathophysiology, University of Erlangen-Nürnberg, 91054 Erlangen, Germany. michael.jm.fischer@meduniwien.ac.at.
Anja-Katrin BosserhoffInstitute of Biochemistry, Emil-Fischer-Center, University of Erlangen-Nürnberg, 91054 Erlangen, Germany. anja.bosserhoff@fau.de.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity Hospital Regensburg · DE

Funding

Deutsche Forschungsgemeinschaft BO1573Deutsche Krebshilfe ABIZKF Erlangen D24, E27
6 · The paper itself

Abstract

(1) Background: Cold atmospheric plasma (CAP) is ionized gas near room temperature. The anti-cancer effects of CAP were confirmed for several cancer types and were attributed to CAP-induced reactive species. However, the mode of action of CAP is still not well understood. (2) Methods: Changes in cytoplasmic Ca

Indexed as

acidificationcalcium signalingcold atmospheric plasmamalignant melanomanitration

Identifiers

PMID31091795
PMCPMC6562457
OpenAlexW2946347237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.