Evidence map›Paper›PMID 31091221›Full record

ArticlePancreas

Epidural Analgesia Improves Postoperative Pain Control but Impedes Early Discharge in Patients Undergoing Pancreatic Surgery.

Stephanie S Kim, Xiaojuan Niu, Irmina A Elliott, Jerry P Jiang, Amanda M Dann, Lauren M Damato, Hallie Chung, Mark D Girgis, Jonathan C King, O Joe Hines and 2 more

Open access · greenAbstract read
In one paragraph

Article in Pancreas. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Epidurals in esophagectomy: end of an era?Journal of thoracic disease · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Stephanie S KimFrom the Departments of Surgery.
Xiaojuan NiuFrom the Departments of Surgery.
Irmina A ElliottFrom the Departments of Surgery.
Jerry P JiangFrom the Departments of Surgery.
Amanda M DannFrom the Departments of Surgery.
Lauren M DamatoFrom the Departments of Surgery.
Hallie ChungFrom the Departments of Surgery.
Mark D GirgisFrom the Departments of Surgery.
Jonathan C KingFrom the Departments of Surgery.
O Joe HinesFrom the Departments of Surgery.
Siamak RahmanAnesthesiology, and.
Timothy R Donahue
University of California, Los Angeles · US

Funding

Pilot and Feasibility ProgramP30DK041301 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROZENGURT, JUAN ENRIQUE · 1990 to 2019
$18.0M
GASTROENTEROLOGYT32DK007180 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JENSEN, DENNIS MICHAEL · 1986 to 2025
$10.0M
NIDDK NIH HHS P30 DK041301NIDDK NIH HHS T32 DK007180
6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate the impact of epidural analgesia (EA) on postoperative length of stay (LOS), expeditious discharge, and pain relief after pancreaticoduodenectomy (PD) and distal pancreatectomy (DP).

methodsRetrospective reviews of 2014-2015 American College of Surgeons National Surgical Quality Improvement Program databases and our institutional pancreatic surgery database were conducted.

resultsOn univariate analysis, EA was associated with statistically significant longer lengths of stay for both PD and DP. On comparative analysis at mode LOS, discharged before versus after 7 days for PD and 6 days for DP, EA was a significant predictor for the longer groups for both procedures on multivariable analysis (PD, odds ratio of 1.465, P < 0.001; DP, odds ratio of 1.471, P = 0.004). On review of our institution's pancreatic surgery database, patient-reported pain scores were significantly lower in the EA groups than intravenous narcotics groups on the day of surgery only for both PD and DP.

conclusionsEpidural analgesia was associated with longer LOS with a most pronounced effect on early discharge after surgery for patients undergoing open PD and DP. It only resulted in superior pain control on the day of surgery.

Indexed as

AgedAnalgesia, EpiduralFemaleHumansLength of StayMaleMiddle AgedPain MeasurementPancreatectomyPancreaticoduodenectomyPatient DischargePostoperative PainRetrospective Studies

Identifiers

PMID31091221
PMCPMC6521855
OpenAlexW2944628679

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.