Evidence map›Paper›PMID 31091143›Full record

ReviewAmerican journal of physiology. Cell physiology2019

Role of extracellular vesicles in stem cell biology.

Stefania Bruno, Giulia Chiabotto, Enrica Favaro, Maria Chiara Deregibus, Giovanni Camussi

Open access · bronzeAbstract readReview
In one paragraph

Review in American journal of physiology. Cell physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The Role of Extracellular Vesicles in Epstein-Barr Virus Immunology and Pathogenesis for Possible Diagnostic and Therapeutic Direction.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Circulating endothelial precursor cells are associated with a healed diabetic foot ulcer evaluated in a prospective cohort study.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2023
    Article
  16. Review
  17. Article
  18. Review
  19. Application of Perinatal Derivatives in Ovarian Diseases.Frontiers in bioengineering and biotechnology · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Stefania BrunoDepartment of Medical Sciences, University of Torino, Turin, Italy.
Giulia ChiabottoDepartment of Medical Sciences, University of Torino, Turin, Italy.
Enrica FavaroDepartment of Medical Sciences, University of Torino, Turin, Italy.
Maria Chiara Deregibus2i3T Business Incubator and Technology Transfer at University of Torino, Turin, Italy.
Giovanni CamussiDepartment of Medical Sciences, University of Torino, Turin, Italy.ORCID 0000-0003-2795-232X
University of Turin · IT

Funding

Regulation of renal and bone marrow injury by extracellular vesicle non-coding RNUH3TR000880 · NCATS · RHODE ISLAND HOSPITAL · PI QUESENBERRY, PETER J. · 2015 to 2017
$1.1M
Regulation of renal and bone marrow injury by extracellular vesicle non-coding RNUH2TR000880 · NCATS · RHODE ISLAND HOSPITAL · PI QUESENBERRY, PETER J. · 2013 to 2014
$498k
NCATS NIH HHS UH2 TR000880NCATS NIH HHS UH3 TR000880
6 · The paper itself

Abstract

The extracellular vesicles (EVs) are membrane vesicles carrying proteins, nucleic acids, and bioactive lipids of the cell of origin. These vesicles released within the extracellular space and entering into the circulation may transfer their cargo to neighboring or distant cells and induce phenotypical and functional changes that may be relevant in several physiopathological conditions. In an attempt to define the biological properties of EVs, several investigations have focused on their cargo and on the effects elicited in recipient cells. EVs have been involved in modulation of tumor microenvironment and behavior, as well as in the immune and inflammatory response. In the present review, we address the paracrine action of EVs released by stem cells and their potential involvement in the activation of regenerative programs in injured cells.

Indexed as

Stem Cell NicheAnimalsExosomesHumansInflammationNeoplasmsNeoplastic Stem CellsParacrine CommunicationSignal TransductionStem CellsTumor Microenvironmentcancer cellsexosomesimmune cellsmicrovesiclesstem cells

Identifiers

PMID31091143
PMCPMC6732418
OpenAlexW2945824415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.