Evidence map›Paper›PMID 31091028›Full record

ArticleThe Journal of clinical psychiatry2019

The 5-Year Course of Medication Treatment in Childhood Anxiety Disorders.

Stephen P Whiteside, Leslie A Sim, Mark W Olsen, Melissa K Hord

Abstract read
In one paragraph

Article in The Journal of clinical psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Cognitive Functioning in Youth with Anxiety Disorders: A Systematic Review.Clinical child and family psychology review · 2024
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Stephen P WhitesideDepartment of Psychiatry and Psychology, Mayo Clinic, 200 First St SW, Rochester, MN 55905. whiteside.stephen@mayo.edu.
Leslie A SimDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA.
Mark W OlsenDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA.
Melissa K HordDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA.
Mayo Clinic · US

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002377
6 · The paper itself

Abstract

objectiveFor pediatric psychiatric disorders, given the marked increase in use of medications without an understanding of the typical treatment course, the primary goal of the current study was to examine the course of pharmacotherapy over 5 years in children with newly diagnosed anxiety disorders.

methodsWe reviewed provider billing and prescription ordering records of a tertiary medical center from 2008 through 2015 to identify children (aged 7-17 years) newly diagnosed with an anxiety disorder and to determine the psychopharmacologic treatment that they received from 2010 through 2015. The frequency at which patients received prescriptions from 9 classes of psychotropic medications at any point during the study period was determined. We used χ² analyses and independent sample t tests to examine the relationship between receiving a psychotropic prescription and various patient characteristics.

resultsThe study cohort included 108 patients (mean [SD] age = 12.8 [3.3] years). In this group, 73.1% received pharmacotherapy on at least 1 occasion over the 5-year period, and 41.7% received medications from more than 1 class. Of those who received a prescription, 50% (27/54) of patients remained on medication for 5 years. This estimate rose to 71% (5/7) within the subset of patients who were medication-naive at the beginning of the observation period and were still in high school during year 5.

conclusionsGuidelines implying discontinuation of medication after symptom remission and a limited period of stability do not accurately reflect clinical practice.

Indexed as

AdolescentAnxiety DisordersChildCohort StudiesDrug Therapy, CombinationFemaleForecastingGermanyGuideline AdherenceHumansMalePractice Patterns, Physicians'Psychotropic DrugsRetrospective StudiesPsychotropic Drugs

Identifiers

PMID31091028
PMCPMC6521862
OpenAlexW2946819940

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.