Evidence map›Paper›PMID 31090999›Full record

ArticleChembiochem : a European journal of chemical biology2019

Protein Spin Labeling with a Photocaged Nitroxide Using Diels-Alder Chemistry.

Anandi Kugele, Bjarne Silkenath, Jakob Langer, Valentin Wittmann, Malte Drescher

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Increasing the Modulation Depth of GdThe journal of physical chemistry letters · 2022
    Article
  8. Article
  9. Chemical communications (Cambridge, England) · 2021
    Article
  10. Article
  11. Article
  12. Protein Spin Labeling with a Photocaged Nitroxide Using Diels-Alder Chemistry.Chembiochem : a European journal of chemical biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anandi KugeleDepartment of Chemistry and, Konstanz Research School Chemical Biology (KoRS-CB), University of Konstanz, Universitätsstrasse 10, 78457, Konstanz, Germany.ORCID 0000-0002-1016-8910
Bjarne SilkenathDepartment of Chemistry and, Konstanz Research School Chemical Biology (KoRS-CB), University of Konstanz, Universitätsstrasse 10, 78457, Konstanz, Germany.ORCID 0000-0001-9862-6076
Jakob LangerDepartment of Chemistry and, Konstanz Research School Chemical Biology (KoRS-CB), University of Konstanz, Universitätsstrasse 10, 78457, Konstanz, Germany.ORCID 0000-0002-0095-1936
Valentin WittmannDepartment of Chemistry and, Konstanz Research School Chemical Biology (KoRS-CB), University of Konstanz, Universitätsstrasse 10, 78457, Konstanz, Germany.ORCID 0000-0003-4043-6813
Malte DrescherDepartment of Chemistry and, Konstanz Research School Chemical Biology (KoRS-CB), University of Konstanz, Universitätsstrasse 10, 78457, Konstanz, Germany.ORCID 0000-0002-3571-3452

Funding

Deutsche Forschungsgemeinschaft SFB 969, Project B5Deutsche Forschungsgemeinschaft SFB 969, Project C3H2020 European Research Council 772027 - SPICE - ERC-2017-COG
6 · The paper itself

Abstract

EPR spectroscopy of diamagnetic bio-macromolecules is based on site-directed spin labeling (SDSL). Herein, a novel labeling strategy for proteins is presented. A nitroxide-based spin label has been developed and synthesized that can be ligated to proteins by an inverse-electron-demand Diels-Alder (DA

Indexed as

Spin LabelsAmino AcidsCycloaddition ReactionElectron Spin Resonance SpectroscopyHumansNitrogen OxidesProteinsAmino AcidsNitrogen OxidesnitroxylProteinsSpin Labelsbioorthogonal chemistrycycloadditionEPR spectroscopynoncanonical amino acidssite-directed spin labeling

Identifiers

PMID31090999
PMCPMC6790680

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.