Evidence map›Paper›PMID 31090826›Full record

SynthesisAnais brasileiros de dermatologia

Tissue healing efficacy in burn patients treated with 1% silver sulfadiazine versus other treatments: a systematic review and meta-analysis of randomized controlled trials.

Alex Bezerra da Silva Maciel, Josmar França Ortiz, Beatriz Santos Siqueira, Gabriela Ferreira Zanette

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  6. Article
  7. Metal Complexes, an Untapped Source of Antibiotic Potential?Antibiotics (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Alex Bezerra da Silva MacielGraduate Studies Program in Tropical Medicine, Universidade do Estado do Amazonas, Manaus (AM), Brazil.ORCID 0000-0002-9836-7868
Josmar França OrtizGraduate Studies Program in Cardiology and Hemodynamics, Faculdade Metropolitana de Manaus, Manaus (AM), Brazil.ORCID 0000-0002-4160-915X
Beatriz Santos SiqueiraUndergraduate student in Pharmacy, Universidade Federal do Amazonas, Manaus (AM), Brazil.ORCID 0000-0002-9155-2251
Gabriela Ferreira ZanetteGraduate Studies Program in Biotechnology, Universidade Federal do Amazonas, Manaus (AM), Brazil.ORCID 0000-0001-8043-7920
Universidade Federal do Amazonas · BRCentro Universitário das Faculdades Metropolitanas Unidas · BRUniversidade do Estado do Amazonas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to evaluate tissue healing efficacy in burn patients treated with 1% silver sulfadiazine versus other treatments. This is a systematic literature review and meta-analysis of randomized clinical trials performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) and PICO strategy, registered in the International Prospective Register of Systematic Reviews (PROSPERO) under the number CRD42017081057. The review found 71 studies in MEDLINE/Pubmed, 1 in Clinical Trials, 19 in the Cochrane Library, and 4 in LILACS in five manual searches. Of these, 81 studies were pre-selected. After independent analysis by two reviewers, only 11 studies met the inclusion criteria for the review. All studies (n = 11) using alternative treatments to silver sulfadiazine were shown to be superior in the mean time for complete wound healing, with statistically significant differences between experimental and control groups (p <0.00001); mean difference (- 4.26), 95% CI [- 5.96, - 2.56].

Indexed as

Wound HealingAnti-Infective Agents, LocalBurnsHospitalizationHumansRandomized Controlled Trials as TopicSilver SulfadiazineTime FactorsTreatment OutcomeAnti-Infective Agents, LocalSilver Sulfadiazine

Identifiers

PMID31090826
PMCPMC6486072
OpenAlexW2944739055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.