Evidence map›Paper›PMID 31090671›Full record

ArticlePsychosomatic medicine2019

Ambulatory Blood Pressure Trajectory and Perceived Stress in Relation to Birth Outcomes in Healthy Pregnant Adolescents.

Julie Spicer, Gerald F Giesbrecht, Sally Aboelela, Seonjoo Lee, Grace Liu, Catherine Monk

Open access · greenAbstract read
In one paragraph

Article in Psychosomatic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Julie SpicerFrom the Department of Psychiatry (Spicer), Icahn School of Medicine at Mount Sinai; Departments of Pediatrics & Community Health Sciences (Giesbrecht), University of Calgary, Alberta, Canada; Departments of Nursing (Aboelela), Psychiatry (Lee, Liu, Monk), and Obstetrics and Gynecology (Monk), Columbia University; and New York State Psychiatric Institute (Monk), New York.
Gerald F Giesbrecht
Sally Aboelela
Seonjoo Lee
Grace Liu
Catherine Monk
Sinai University · EGBridge University · SS

Funding

The Effects of Prenatal Stress & Poor Nutrition on Brain and CognitionR01MH093677 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MONK, CATHERINE E, PETERSON, BRADLEY S · 2011 to 2015
$3.4M
SES and ALLOSTATIC Load: Pregnancy Outcomes and Maternal NeurobehaviorR00HD079668 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SPICER, JULIE A · 2017 to 2019
$747k
SES and ALLOSTATIC Load: Pregnancy Outcomes and Maternal NeurobehaviorK99HD079668 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SPICER, JULIE A · 2015 to 2017
$282k
NICHD NIH HHS K99 HD079668NICHD NIH HHS R00 HD079668NIMH NIH HHS R01 MH093677
6 · The paper itself

Abstract

objectiveAn early decline in resting blood pressure (BP), followed by an upward climb, is well documented and indicative of a healthy pregnancy course. Although BP is considered both an effector of stress and a clinically meaningful measurement in pregnancy, little is known about its trajectory in association with birth outcomes compared with other stress effectors. The current prospective longitudinal study examined BP trajectory and perceived stress in association with birth outcomes (gestational age (GA) at birth and birth weight (BW) percentile corrected for GA) in pregnant adolescents, a group at risk for stress-associated poor birth outcomes.

methodsHealthy pregnant nulliparous adolescents (n = 139) were followed from early pregnancy through birth. At three time points (13-16, 24-27, and 34-37 gestational weeks ±1 week), the Perceived Stress Scale was collected along with 24-hour ambulatory BP (systolic and diastolic) and electronic diary reporting of posture. GA at birth and BW were abstracted from medical records.

resultsAfter adjustment for posture and pre-pregnancy body mass index, hierarchical mixed-model linear regression showed the expected early decline (B = -0.18, p = .023) and then increase (B = 0.01, p < .001) of diastolic BP approximating a U-shape; however, systolic BP displayed only an increase (B = 0.01, p = .010). In addition, the models indicated a stronger systolic and diastolic BP U-shape for early GA at birth and lower BW percentile and an inverted U-shape for late GA at birth and higher BW percentile. No effects of perceived stress were observed.

conclusionsThese results replicate the pregnancy BP trajectory from previous studies of adults and indicate that the degree to which the trajectory emerges in adolescence may be associated with variation in birth outcomes, with a moderate U-shape indicating the healthiest outcomes.

Indexed as

Gestational AgePregnancy OutcomeAdolescentBirth WeightBlood PressureBlood Pressure Monitoring, AmbulatoryFemaleHumansLongitudinal StudiesPregnancyPregnancy ComplicationsPregnancy in AdolescenceStress, Psychological

Identifiers

PMID31090671
PMCPMC6715293
OpenAlexW2938352926

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.