Evidence map›Paper›PMID 31090541›Full record

ArticleeLife2019

Stem cell topography splits growth and homeostatic functions in the fish gill.

Julian Stolper, Elizabeth Mayela Ambrosio, Diana-Patricia Danciu, Lorena Buono, David A Elliott, Kiyoshi Naruse, Juan R Martínez-Morales, Anna Marciniak-Czochra, Lazaro Centanin

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Improve your success with fish cell lines-small things that matter.In vitro cellular & developmental biology. Animal · 2026
    Review
  2. Regeneration in fish, with special focus on killifishes.Fish physiology and biochemistry · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Craniofacial developmental biology in the single-cell era.Development (Cambridge, England) · 2023
    Review
  9. Tissue Homeostasis and Non-Homeostasis: From Cell Life Cycles to Organ States.Annual review of cell and developmental biology · 2022
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 5 countries.

Julian StolperCentre for Organismal Studies, Heidelberg University, Heidelberg, Germany.
Elizabeth Mayela AmbrosioCentre for Organismal Studies, Heidelberg University, Heidelberg, Germany.ORCID 0000-0001-7227-7744
Diana-Patricia DanciuInstitute of Applied Mathematics, Heidelberg University, Heidelberg, Germany.ORCID 0000-0002-8683-3956
Lorena BuonoCentro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide, Seville, Spain.
David A ElliottMurdoch Children's Research Institute, Royal Children's Hospital, Parkville, Australia.ORCID 0000-0003-1052-7407
Kiyoshi NaruseLaboratory of Bioresources, National Institute for Basic Biology, National Institutes of Natural Sciences, Okazaki, Japan.
Juan R Martínez-MoralesCentro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide, Seville, Spain.ORCID 0000-0002-4650-4293
Anna Marciniak-CzochraInstitute of Applied Mathematics, Heidelberg University, Heidelberg, Germany.ORCID 0000-0002-5831-6505
Lazaro CentaninCentre for Organismal Studies, Heidelberg University, Heidelberg, Germany.ORCID 0000-0003-3889-4524
Heidelberg University · DECentro Andaluz de Biología del Desarrollo · ESRoyal Children's Hospital · AUNational Institute for Basic Biology · JPUniversity of Copenhagen · DK

Funding

Deutsche Forschungsgemeinschaft SFB873/A11Deutsche Forschungsgemeinschaft SFB873/B08University of Melbourne Melbourne Research Fellowship / Graduate Student Fellowship
6 · The paper itself

Abstract

While lower vertebrates contain adult stem cells (aSCs) that maintain homeostasis and drive un-exhaustive organismal growth, mammalian aSCs display mainly the homeostatic function. Here, we use lineage analysis in the medaka fish gill to address aSCs and report separate stem cell populations for homeostasis and growth. These aSCs are fate-restricted during the entire post-embryonic life and even during re-generation paradigms. We use chimeric animals to demonstrate that

Indexed as

Adipose TissueAdult Stem CellsAnimalsCell DifferentiationChimeraGenes, p53GillsHomeostasisHumansOryziasStem Cell Nicheadult stem cellsdevelopmental biologyfate-restrictiongrowth coordinationlineage analysismedakaorgan growthregenerative medicinestem cells

Identifiers

PMID31090541
PMCPMC6534379
OpenAlexW2902334717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.