ReviewJournal of Zhejiang University. Science. B2019
Genomic data mining for functional annotation of human long noncoding RNAs.
Review in Journal of Zhejiang University. Science. B, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- RNA-Lexis: a probabilistic algorithm using a non-parametric segmentation logic to detect meaningful sequences in RNA.Nucleic acids research · 2026Article
- Ischemic Stroke and Autophagy: The Roles of Long Non-Coding RNAs.Current neuropharmacology · 2024Review
- LncRNA MHRT Prevents Angiotensin II-Induced Myocardial Oxidative Stress and NLRP3 Inflammasome via Nrf2 Activation.Antioxidants (Basel, Switzerland) · 2023Article
- The long non-coding RNA transcript, LOC100130460 (CAND1.11) gene, encodes a novel protein highly expressed in cancer cells and tumor human testis tissues.Cancer biomarkers : section A of Disease markers · 2023Article
- Integrative analysis of prognostic long non-coding RNAs with copy number variation in bladder cancer.Journal of Zhejiang University. Science. B · 2021Article
- Different Data Mining Approaches Based Medical Text Data.Journal of healthcare engineering · 2021Review
- Prediction and prioritization of autism-associated long non-coding RNAs using gene expression and sequence features.BMC bioinformatics · 2020Article
- Deep analysis of RNA NNAR genomics and bioinformatics · 2020Article
- Knockdown of PVT1 Suppresses Colorectal Cancer Progression by Regulating MiR-106b-5p/FJX1 Axis.Cancer management and research · 2020Article
- Expression Profiles of Long Noncoding RNAs in Mice with High-Altitude Hypoxia-Induced Brain Injury Treated withNeuropsychiatric disease and treatment · 2020Article
- A special issue to mark the 90th Anniversary of College of Life Sciences, Zhejiang University.Journal of Zhejiang University. Science. B · 2019Article
- A Novel Protein Subcellular Localization Method With CNN-XGBoost Model for Alzheimer's Disease.Frontiers in genetics · 2018Article
- Comparative transcriptomic analysis of vascular endothelial cells after hypoxia/re-oxygenation induction based on microarray technology.Journal of Zhejiang University. Science. BArticle
- Role of LINC00152 in non-small cell lung cancer.Journal of Zhejiang University. Science. BArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Life may have begun in an RNA world, which is supported by increasing evidence of the vital role that RNAs perform in biological systems. In the human genome, most genes actually do not encode proteins; they are noncoding RNA genes. The largest class of noncoding genes is known as long noncoding RNAs (lncRNAs), which are transcripts greater in length than 200 nucleotides, but with no protein-coding capacity. While some lncRNAs have been demonstrated to be key regulators of gene expression and 3D genome organization, most lncRNAs are still uncharacterized. We thus propose several data mining and machine learning approaches for the functional annotation of human lncRNAs by leveraging the vast amount of data from genetic and genomic studies. Recent results from our studies and those of other groups indicate that genomic data mining can give insights into lncRNA functions and provide valuable information for experimental studies of candidate lncRNAs associated with human disease.
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Registered trials
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