ReviewPeriodontology 20002019
Noma (cancrum oris): An unresolved global challenge.
Review in Periodontology 2000, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Prevalence and associated risk factors for noma in Nigerian children: a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents.Journal of clinical periodontology · 2026Review
- Systematic scoping review of the noma evidence landscape: current knowledge and gaps.BMJ global health · 2025Article
- Estimated incidence and clinical presentation of Noma in Northern Nigeria (1999-2024).PLoS neglected tropical diseases · 2025Article
- Noma in the WHO's list of neglected tropical diseases: A review of its impact on undeveloped and developing tropical regions.Preventive medicine reports · 2024Review
- Noma in an 18 months Toddler: A Rare Case Report with Review of Literature.Journal of maxillofacial and oral surgery · 2024Article
- Noma: a PubMed-based informetric analysis of a neglected tropical orofacial disease in Nigeria.Sudanese journal of paediatrics · 2023Article
- The key players of dysbiosis in Noma disease; A systematic review of etiological studies.Frontiers in oral health · 2023Review
- An unusual cause of facial wound in a child: Hyper IgE syndrome-associated Noma neonatorum.International wound journal · 2022Article
- Is noma a neglected/overlooked tropical disease?Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022Article
- Paediatric Deep Neck Infection-The Risk of Needing Intensive Care.Children (Basel, Switzerland) · 2022Review
- Noma staging: a review.Tropical medicine and health · 2022Review
- Noma (cancrum oris): A scoping literature review of a neglected disease (1843 to 2021).PLoS neglected tropical diseases · 2021Article
- Review
- Columella reconstruction using double nasolabial flap and costal cartilage: A case report.Annals of medicine and surgery (2012) · 2021Article
- Case Report: Malignant Transformation of Noma: Repair by Forearm Flap.The American journal of tropical medicine and hygiene · 2020Article
- Noma (cancrum oris): An unresolved global challenge.Periodontology 2000 · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Noma (canrum oris) is a mutilating necrotizing disease of uncertain etiology, but it is accepted that it is caused primarily by a polybacterial infection with secondary ischemia. The consequent necrotizing fasciitis, myonecrosis, and osteonecrosis results in destruction of facial structures with severe functional impairment and disfigurement. It most frequently affects children, particularly in sub-Saharan Africa, who are malnourished or debilitated by systemic conditions including but not limited to malaria, measles, and tuberculosis; and less frequently debilitated HIV-seropositive subjects. In the vast majority of cases, in susceptible subjects, noma is preceded by necrotizing stomatitis. However, it has been reported, albeit rarely, that noma can arise without any preceding oral lesions being observed. Noma is not recurrent and is not transmissible.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.