ArticleInternational urology and nephrology2019
Twenty-four-hour urine osmolality as a representative index of adequate hydration and a predictor of recurrence in patients with urolithiasis.
Article in International urology and nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Article
- Correlation Between Stone Composition and Serum Metabolic Abnormalities in Recurrent Renal Calculi.Cureus · 2025Article
- Predicting urinary stone recurrence: a joint model analysis of repeated 24-hour urine collections from the MSTONE database.Urolithiasis · 2024Article
- Screen-Printed Wearable Sweat Sensor for Cost-Effective Assessment of Human Hydration Status through Potassium and Sodium Ion Detection.Micromachines · 2023Article
- How to Monitor Hydration Status and Urine Dilution in Patients with Nephrolithiasis.Nutrients · 2023Review
- Diagnostic value of urinary Tamm-Horsfall protein and 24 h urine osmolality for recurrent calcium oxalate stones of the upper urinary tract: Cross-sectional study.Open medicine (Warsaw, Poland) · 2023Article
- Twenty-four-hour urine osmolality should be used in combination with other urine parameters in urolithiasis patients.International urology and nephrology · 2019Article
- Response to the letter to editor: 24-h urine osmolality should be used in combination with other urine parameters in urolithiasis patients.International urology and nephrology · 2019Article
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8 authors.
Funding
Abstract
purposeTo determine the value of 24-h urine osmolality (UOsm) as a representative index of adequate hydration and predictor of stone recurrence in patients with urolithiasis.
methodsMedical records of consecutive patients presenting with renal or ureteric stones between 1994 and 2017 were retrospectively reviewed. Patients were grouped according to the results of 24-h UOsm (low ≤ 564 mOsm/kg H
resultsThe low urine concentration group were more likely to be older, to be female, and to have a lower body mass index and higher glomerular filtration rate than the high concentration group (each P < 0.005). A positive correlation was seen between 24-h UOsm and urinary calcium, sodium, uric acid, and magnesium excretion and 24-h specific gravity; a negative correlation was seen with 24-h urine volume. Stone-forming constituents, such as calcium and uric acid, were significantly higher in the high urine concentration group. Kaplan-Meier estimates showed that the low urine concentration group had a significantly longer stone recurrence-free period than the high urine concentration group (log-rank test, P < 0.001). In multivariate Cox regression analyses, 24-h UOsm was seen to be an independent risk factor for stone recurrence.
conclusionsUOsm is a promising approach to assessing hydration and predicting stone recurrence in patients with urolithiasis. Maintaining UOsm < 564 mOsm/kg H
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