Evidence map›Paper›PMID 31089937›Full record

ArticleJournal of clinical immunology2019

IKZF1 Loss-of-Function Variant Causes Autoimmunity and Severe Familial Antiphospholipid Syndrome.

Yannick Dieudonné, Aurélien Guffroy, Olivier Vollmer, Raphael Carapito, Anne-Sophie Korganow

Abstract readCase ReportsLetter
PubMed Publisher
In one paragraph

Article in Journal of clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. IKZF-associated inborn errors of immunity.Journal of human immunity · 2025
    Review
  3. Article
  4. Article
  5. Infections in Disorders of Immune Regulation.Pathogens (Basel, Switzerland) · 2024
    Review
  6. Multifaceted roles ofFrontiers in oncology · 2024
    Review
  7. IKAROS Family Transcription Factors in Lymphocyte Differentiation and Function.Advances in experimental medicine and biology · 2024
    Review
  8. Review
  9. Pathogenic germlineCold Spring Harbor molecular case studies · 2021
    Article
  10. GermlineExpert review of clinical immunology · 2021
    Review
  11. Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yannick DieudonnéCNRS UPR 3572, Immunopathology and Therapeutic Chemistry, Laboratory of Excellence Medalis, Institute of Molecular and Cellular Biology (IBMC), 15 rue René Descartes, 67084, Strasbourg Cedex, France.
Aurélien GuffroyCNRS UPR 3572, Immunopathology and Therapeutic Chemistry, Laboratory of Excellence Medalis, Institute of Molecular and Cellular Biology (IBMC), 15 rue René Descartes, 67084, Strasbourg Cedex, France.ORCID 0000-0003-0615-5305
Olivier VollmerDepartment of Clinical Immunology and Internal Medicine, National Reference Center for Autoimmune Diseases, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Raphael CarapitoUFR Médecine, Université de Strasbourg, Strasbourg, France.
Anne-Sophie KorganowCNRS UPR 3572, Immunopathology and Therapeutic Chemistry, Laboratory of Excellence Medalis, Institute of Molecular and Cellular Biology (IBMC), 15 rue René Descartes, 67084, Strasbourg Cedex, France. korganow@unistra.fr.
Centre National de la Recherche Scientifique · FRHôpitaux Universitaires de Strasbourg · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Loss of Function MutationAdolescentAllelesAntiphospholipid SyndromeAutoantibodiesAutoimmunityBiomarkersExome SequencingFemaleGenetic LociGenotypeHumansIkaros Transcription FactorImmunoglobulins, IntravenousImmunophenotypingMagnetic Resonance ImagingAutoantibodiesBiomarkersIkaros Transcription FactorIKZF1 protein, humanImmunoglobulins, Intravenous

Identifiers

PMID31089937
OpenAlexW2945460208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.