Evidence map›Paper›PMID 31089883›Full record

ArticlePediatric surgery international2019

Outcomes of infants with congenital diaphragmatic hernia by side of defect in the FETO era.

Kamal Ali, Theodore Dassios, Syed Abdul Khaliq, Emma E Williams, Kentaro Tamura, Mark Davenport, Anne Greenough

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric surgery international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Perinatal Outcomes after Fetal Endoscopic Tracheal Occlusion for Isolated Congenital Diaphragmatic Hernia: Rapid Review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Unsolved problems in CDH follow-up.Frontiers in pediatrics · 2022
    Article
  8. Article
  9. Predicting treatment of pulmonary hypertension at discharge in infants with congenital diaphragmatic hernia.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kamal AliNeonatal Intensive Care Centre, 4th Floor Golden Jubilee Wing, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK.
Theodore DassiosNeonatal Intensive Care Centre, 4th Floor Golden Jubilee Wing, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK.
Syed Abdul KhaliqNeonatal Intensive Care Centre, 4th Floor Golden Jubilee Wing, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK.
Emma E WilliamsWomen and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Kentaro TamuraNeonatal Intensive Care Centre, 4th Floor Golden Jubilee Wing, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK.
Mark DavenportDepartment of Paediatric Surgery, King's College Hospital NHS Foundation Trust, London, UK.
Anne GreenoughNeonatal Intensive Care Centre, 4th Floor Golden Jubilee Wing, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK. anne.greenough@kcl.ac.uk.ORCID http://orcid.org/0000-0002-8672-5349

Funding

NIHR Biomedical Research Centre based at Guy's and St Thomas NHS Foundation Trust and King's College London N/A
6 · The paper itself

Abstract

purposeTo compare the outcomes of infants with a right (RCDH) versus a left-sided (LCDH) congenital diaphragmatic hernia (CDH) and whether these differed according to whether the infants had undergone fetoscopic tracheal occlusion (FETO).

methodsDemographics, the type of surgical repair, preoperative and postoperative courses and respiratory, gastrointestinal, surgical and skeletal morbidities at follow-up were compared between infants with a RCDH or LCDH. A sub-analysis was undertaken in those who had undergone FETO.

resultsDuring the study period, there were 167 infants with a LCDH and 24 with a RCDH; 106 underwent FETO (15 RCDH). Overall, the need for inhaled nitric oxide (p = 0.036) was higher in the RCDH group and, at follow-up, infants with RCDH were more likely to have a hernia recurrence (p = 0.043), pectus deformity (p = 0.019), scoliosis (p = 0.029) and suffer chronic respiratory morbidity (p = 0.001). There were, however, no significant differences in short term or long term outcomes (hernia recurrence (p = 0.237), pectus deformity (p = 0.322), scoliosis (p = 0.0174) or chronic respiratory morbidity (p = 0.326)) between infants with a right or left sided CDH who had undergone FETO.

conclusionOverall, infants with a RCDH compared to those with a LCDH had greater long-term morbidity, but not if they had undergone FETO.

Indexed as

FemaleFetoscopyFollow-Up StudiesGestational AgeHernias, Diaphragmatic, CongenitalHerniorrhaphyHumansInfant, NewbornMalePregnancyRecurrenceRetrospective StudiesSurvival RateUnited KingdomCongenital diaphragmatic herniaFollow-upHernia recurrenceSurvival

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.