ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2019
Paediatric intracranial aneurysms: a British institutional review.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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6 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Treatment of pediatric intracranial aneurysms: institutional case series and systematic literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Pooled it
- Microsurgical clipping of large MCA aneurysm in a 2-month-old child.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Pediatric anterior choroidal artery aneurysm successfully coiled after re-rupture.The neuroradiology journal · 2024Article
- Pediatric intracranial aneurysms in a Southern Brazilian population.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Observational
- Should we screen for intracranial aneurysms in children with autosomal dominant polycystic kidney disease?Pediatric nephrology (Berlin, Germany) · 2023Article
- Risk factors for intracranial aneurysm rupture in pediatric patients.Acta neurochirurgica · 2022Article
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Authors and funding
8 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
introductionPaediatric intracranial aneurysms are rare, with a differing natural history and thought to account for only up to 7% of all intracranial aneurysms. There is much uncertainty that surrounds the prevalence of unruptured intracranial aneurysms and it is estimated to be anywhere between 2 and 90 per 1000. This is the largest British single-centre analysis of paediatric intracranial aneurysms. We present the patient course from their initial presentations to the outcome of treatment and evaluate a serial assessment of adequacy of aneurysmal obliteration radiologically.
resultsTwenty-two paediatric cases were identified that required treatment. The median age of presentation was 11.3 years (mean 9.9, range 0 to 15.9), 68% (15/22) were male and 77% (17/22) were ruptured on presentation. The majority of aneurysms were located at the anterior circulation (77% (17/22)). The overall median aneurysm size (n = 21) was 7.4 mm (mean 5 mm, range 2.5-19 mm). Twenty patients survived the acute phase and 80% (16/20) underwent coil embolisation and the other patients' surgical clipping. The overall outcomes were available for the 20 patients; on discharge, 90% (18/20) had a favourable clinical outcome (GOS score of 3-5). Treatment-specific clinical favourable outcomes were 88% (14/16) for coil embolisation against 100% (4/4) after surgical clipping. Of the two patients that died in the acute phase, one had sickle cell anaemia. Aneurysm aetiology was unknown in all other cases. None of the patients had a family history of aneurysms.
conclusionPaediatric intracranial aneurysms while rare should be considered a differential diagnosis of children presenting with unexplained loss of consciousness with or without focal neurological deficit and/or headache. There is a two to one preponderance for males with a larger proportion of aneurysms within the posterior circulation (25%). Coil embolisation is the preferred method of securing a paediatric intracranial aneurysm.
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