Evidence map›Paper›PMID 31089822›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2019

The role of halogen substituents and substrate pK

Julia E Burrows, Monica Q Paulson, Emma R Altman, Ivana Vukovic, Timothy E Machonkin

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Characterization of the substrate specificity and regioselectivity of ring-cleavage of Pseudomonas putida DLL-E4 hydroquinone 1,2-dioxygenase (PnpC1C2).Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Julia E BurrowsDepartment of Chemistry, Whitman College, 345 Boyer Ave, Walla Walla, WA, 99362, USA.
Monica Q PaulsonDepartment of Chemistry, Whitman College, 345 Boyer Ave, Walla Walla, WA, 99362, USA.
Emma R AltmanDepartment of Chemistry, Whitman College, 345 Boyer Ave, Walla Walla, WA, 99362, USA.
Ivana VukovicDepartment of Chemistry, Whitman College, 345 Boyer Ave, Walla Walla, WA, 99362, USA.
Timothy E MachonkinDepartment of Chemistry, Whitman College, 345 Boyer Ave, Walla Walla, WA, 99362, USA. machonte@whitman.edu.
Whitman College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2,6-Dichlorohydroquinone 1,2-dioxygenase (PcpA) is a non-heme Fe(II) enzyme that is specific for ortho-dihalohydroquinones. Here we deconvolute the role of halogen polarizability vs. substrate pK

Indexed as

AnaerobiosisDioxygenasesHalogensHydrogen-Ion ConcentrationHydroquinonesKineticsSubstrate Specificity2,6-dichlorohydroquinone dioxygenaseDioxygenasesHalogensHydroquinonesHalogen bondingHydroquinone dioxygenaseKineticspK aTitration

Identifiers

PMID31089822
OpenAlexW2537649779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.