Evidence map›Paper›PMID 31089772›Full record

ReviewCalcified tissue international2020

Vitamin D, and Maternal and Child Health.

Rebecca J Moon, Justin H Davies, Cyrus Cooper, Nicholas C Harvey

Open access · hybridAbstract readReview
In one paragraph

Review in Calcified tissue international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. The effect of pregnancy vitamin D supplementation on offspring bone mineral density in childhood: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
    Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Cutoff value of serum 25-hydroxyvitamin D leading to vitamin D deficiency for children in Japan.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Nutritional risks in children with food allergy.Turkish journal of medical sciences · 2023
    Article
  16. Review
  17. Article
  18. Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Rebecca J MoonMRC Lifecourse Epidemiology Unit, Southampton General Hospital, University of Southampton, Southampton, SO16 6YD, UK.
Justin H DaviesPaediatric Endocrinology, University Hospitals Southampton NHS Foundation Trust, Southampton, UK.
Cyrus CooperMRC Lifecourse Epidemiology Unit, Southampton General Hospital, University of Southampton, Southampton, SO16 6YD, UK.
Nicholas C HarveyMRC Lifecourse Epidemiology Unit, Southampton General Hospital, University of Southampton, Southampton, SO16 6YD, UK. nch@mrc.soton.ac.uk.
MRC Lifecourse Epidemiology Unit · GBNational Institute for Health Research · GBUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

Biotechnology and Biological Sciences Research Council BB/P028179/1Department of Health 10/33/04Medical Research Council 4050502589Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Versus Arthritis 17702Versus Arthritis 21231
6 · The paper itself

Abstract

Vitamin D has important roles in calcium metabolism and in the prevention of rickets and osteomalacia; low levels of 25-hydroxyvitamin D are common in the general population and amongst pregnant women. Whilst there is a wealth of observational evidence linking vitamin D deficiency to a wide range of disease outcomes, there are currently few high-quality randomised controlled trials to confirm any causal associations, although many are currently in progress. Furthermore, currently, the vast majority of published guidelines recommend standard supplemental vitamin D doses for children and pregnant women, yet there is increasing recognition that individual characteristics and genetic factors may influence the response to supplementation. As such, future research needs to concentrate on documenting definite beneficial clinical outcomes of vitamin D supplementation, and establishing personalised dosing schedules and demonstrating effective approaches to optimising initiation and adherence.

Indexed as

Calcium, DietaryDietary SupplementsFemaleHumansPregnancyPregnancy ComplicationsVitamin DVitamin D DeficiencyVitaminsCalcium, DietaryVitamin DVitaminsBone mineral densityPregnancyRicketsSupplementationVitamin D

Identifiers

PMID31089772
PMCPMC7019685
OpenAlexW2945970894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.