ReviewAdvances in nutrition (Bethesda, Md.)2019
Milk and Dairy Product Consumption and Prostate Cancer Risk and Mortality: An Overview of Systematic Reviews and Meta-analyses.
Review in Advances in nutrition (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- 2022 Update on Prostate Cancer Epidemiology and Risk Factors-A Systematic Review.European urology · 2023Pooled it
- Pooled it
- Risk factors for bronchiectasis in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis.Clinics (Sao Paulo, Brazil) · 2021Pooled it
- Attitudes and adherence to changes in nutrition and physical activity following surgery for prostate cancer: a qualitative study.BMJ open · 2022Trial
- A recipe for a disaster: food, climate change, and cancer.Cancer causes & control : CCC · 2025Review
- The Impact of Diet and Nutrition on Prostate Cancer - Food for Thought?Current oncology reports · 2025Review
- Global burden and risk factors of male cancers from 1990 to 2021, with forecasts to 2040.Scientific reports · 2025Article
- The Role of Dairy in Human Nutrition: Myths and Realities.Nutrients · 2025Review
- Global burden and trends analysis of common cancers attributable to dietary risks from 1990 to 2021 and projection to 2050: a secondary analysis for the global burden of disease study 2021.Frontiers in nutrition · 2025Article
- Percentage of fat in milk consumption and risk of six cancers: a Mendelian randomization study.Translational cancer research · 2024Article
- Skimmed milk intake reduces the risk of ER- breast cancer: a Mendelian randomization analysis.Discover oncology · 2024Article
- Differential association between dairy intake patterns and incident prostate cancer: a potential dairy matrix effect.European journal of nutrition · 2024Article
- Examining the Role of Nutrition in Cancer Survivorship and Female Fertility: A Narrative Review.Current developments in nutrition · 2024Review
- The Dairy and Cancer Controversy: Milking the Evidence.Current oncology reports · 2024Review
- Sex steroid hormone residues in milk and their potential risks for breast and prostate cancer.Frontiers in nutrition · 2024Review
- Association between Healthy Eating Index-2015 and prostate enlargement: A cross-sectional study of the National and Nutrition Examination Survey 2001-2008.Food & nutrition research · 2024Article
- Dairy product consumption and lung cancer risk: A prospective analysis.Clinical nutrition ESPEN · 2023Article
- Lifestyle aspects in a contemporary middle-European cohort of patients undergoing androgen deprivation therapy for advanced prostate cancer: data from the non-interventional LEAN study.The British journal of nutrition · 2023Observational
- Low-fat dairy consumption and the risk of lung cancer: A large prospective cohort study.Cancer medicine · 2023Article
- Protein and amino acid intakes in relation to prostate cancer risk and mortality-A prospective study in the European Prospective Investigation into Cancer and Nutrition.Cancer medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Milk and dairy product consumption has been associated with an increase in prostate cancer risk; however, discrepancies have been observed in the literature. This first overview of systematic reviews and meta-analyses was carried out with the main objective of compiling and discussing the evidence generated to date related to milk and dairy product consumption and prostate cancer risk and mortality. A systematic search in MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, the Cochrane Database of Systematic Reviews, and the Web of Science (from inception to 30 April 2018) was conducted. The inclusion criteria were as follows: adult men, meta-analyses of longitudinal studies, dairy product consumption, and risk of prostate cancer or related outcomes. The AMSTAR2 checklist was used to evaluate methodological quality. The synthesis methods included dairy product exposure (high compared with low consumption or dose-response), dairy product type (total dairy products, milk, cheese, yogurt, and others), and prostate cancer outcomes (total, nonadvanced, and advanced prostate cancer and mortality) displayed in forest plots. Six meta-analyses were identified. These studies reported on the analysis of the 2 to 32 cohorts (up to 848,395 subjects/38,107 cases; 4-28 y of follow-up) and 2 case-control meta-analyses (12,435 subjects). The meta-analysis quality was valued as mostly "good" according to the AMSTAR2 criteria. All RRs of high compared with low consumption (dose-response) for total prostate cancer ranged from 1.68 to 1.09 (1.07 per 400 g/d) for total dairy products, 1.50 to 0.92 (1.06 to 0.98 per 200 g/d) for milk (whole, low-fat, and skim milk considered separately), and 1.18 to 0.74 (1.10 per 50 g/d) for cheese. RRs have decreased since the first meta-analysis. Statistical heterogeneity generates uncertainty in the observed results (up to I2 = 77.1%). In conclusion, although there are some data indicating that higher consumption of dairy products could increase the risk of prostate cancer, the evidence is not consistent. This review was registered with PROSPERO as CRD42018094737.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.