ArticleScientific reports2019
Mortality rate-dependent variations in the survival without major morbidities rate of extremely preterm infants.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Prevalence of survival without major morbidity and associated risk factors among very preterm infants: a systematic review and meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Stem cells for bronchopulmonary dysplasia in preterm infants: A randomized controlled phase II trial.Stem cells translational medicine · 2021Trial
- Variations in survival outcomes of infants born at 22-23 weeks' gestation by neonatal intensive care quality level in Korea.Scientific reports · 2026Article
- Necrotizing enterocolitis in very preterm infants: an epidemiological study in Jiangsu, China.Frontiers in pediatrics · 2026Article
- The current clinical landscape of preterm infants less than 32 weeks of gestation receiving delivery room chest compression in Jiangsu Province, China.Resuscitation plus · 2025Article
- The current clinical landscape of neonatal respiratory failure in Jiangsu Province of China: patient demographics, NICU treatment interventions, and patient outcomes.BMC pediatrics · 2024Article
- Serum cytokines in second trimester pregnancy and their relationship with spontaneous preterm births in the Ribeirão Preto and São Luiz cohorts.BMC pregnancy and childbirth · 2023Article
- Severe intraventricular hemorrhage causes long-lasting structural damage in a preterm rabbit pup model.Pediatric research · 2022Article
- Serial Short-Term Outcomes of Very-Low-Birth-Weight Infants in the Korean Neonatal Network From 2013 to 2020.Journal of Korean medical science · 2022Article
- Cesarean section was not associated with mortality or morbidities advantage in very low birth weight infants: a nationwide cohort study.Scientific reports · 2021Article
- A multicenter retrospective study on survival rate and complications of very preterm infants.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Neonatal Outcomes according to the Latent Period from Membrane Rupture to Delivery among Extremely Preterm Infants Exposed to Preterm Premature Rupture of Membrane: a Nationwide Cohort Study.Journal of Korean medical science · 2021Article
- Mortality and Morbidities according to Time of Birth in Extremely Low Birth Weight Infants.Journal of Korean medical science · 2021Article
- Survival rate dependent variations in retinopathy of prematurity treatment rates in very low birth weight infants.Scientific reports · 2020Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effects of improved survival of EPT infants on morbidity among survivors remain largely controversial. This retrospective cohort study of the Korean Neonatal Network data investigated whether the mortality rate of 23-24 weeks' gestation was associated with survival without major morbidities in periviable 25-26 weeks' gestation infants. The 2,083 eligible infants with 23-26 weeks' gestation were grouped based on institutional mortality rate (group 1 and 2 ≤50% and >50% mortality rate, respectively, for 23-24 weeks' gestation) and were further divided into 23-24 and 25-26 weeks' gestation subgroups. The mortality rate of 23-24 weeks' gestation infants was significantly lower in group 1 (32.7%) than in group 2 (69.9%). The survival without major morbidities rate for 25-26 weeks' gestation infants was significantly higher in group 1 (31.2%) than in group 2 (18.5%). Antenatal steroid use and Apgar score at 5 min in group 1 were associated with decreased mortality and survival without major morbidities in 23-24 and 25-26 weeks' gestation infants, respectively. In the multivariate analyses, decreased mortality rates in 23-24 weeks' gestation infants were associated with higher survival without major morbidities rates in 25-26 weeks' gestation infants due to decreased bronchopulmonary dysplasia, periventricular leukomalacia, and late-onset sepsis. Evidence-based perinatal and neonatal practices, including antenatal steroid use and better delivery room care contributing to decreased mortality in periviable 23-24 weeks' gestation infants, were associated with lower morbidity and higher survival without major morbidities in more mature 25-26 weeks' gestation infants.
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