Evidence map›Paper›PMID 31089249›Full record

ArticleLeukemia2019

Phase 1 first-in-human trial of the anti-CD37 antibody BI 836826 in relapsed/refractory chronic lymphocytic leukemia.

Stephan Stilgenbauer, Thérèse Aurran Schleinitz, Barbara Eichhorst, Fabian Lang, Fritz Offner, Jean-François Rossi, Wilfried Schroyens, Eric Van Den Neste, Loïc Ysebaert, Ute von Wangenheim and 3 more

Abstract readClinical Trial, Phase ILetter
PubMed Publisher
In one paragraph

Article in Leukemia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Current state of CAR-T therapy for T-cell malignancies.Therapeutic advances in hematology · 2022
    Review
  9. Article
  10. Article
  11. NK Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications.International journal of molecular sciences · 2021
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stephan StilgenbauerDepartment of Internal Medicine III, Ulm University, 89081, Ulm, Germany. Stephan.Stilgenbauer@uniklinik-ulm.de.
Thérèse Aurran SchleinitzDepartment of Hematology, Institute Paoli-Calmettes, Marseille, France.
Barbara EichhorstDepartment I of Internal Medicine, Center for Integrated Oncology Cologne Bonn, University of Cologne, Cologne, Germany.
Fabian LangDepartment of Hematology/Oncology, Goethe University Hospital, Frankfurt am Main, Germany.
Fritz OffnerUniversitair Ziekenhuis Gent, Gent, Belgium.
Jean-François RossiDépartement d'Hématologie Clinique, CHU Montpellier, Université Montpellier, 80 Avenue Augustin Fliche, 34295, Montpellier, France.
Wilfried SchroyensAntwerp University Hospital and University of Antwerp, Antwerp, Belgium.
Eric Van Den NesteDepartment of Hematology, Cliniques Universitaires Saint-Luc & Université Catholique de Louvain, B-1200, Brussels, Belgium.
Loïc YsebaertIUCT-Oncopole, Toulouse, France.
Ute von WangenheimBoehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
Uta Ursula KressBoehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
Petra BlumBoehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
Thorsten ZenzDepartment of Medicine V, University Hospital Heidelberg, Department of Molecular Therapy in Haematology & Oncology, NCT/DKFZ, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overAntibodies, Monoclonal, HumanizedAntigens, NeoplasmAntineoplastic Agents, ImmunologicalAntineoplastic Combined Chemotherapy ProtocolsFemaleHumansLeukemia, Lymphocytic, Chronic, B-CellLymphoma, B-CellMaleMiddle AgedTetraspaninsAntibodies, Monoclonal, HumanizedAntigens, NeoplasmAntineoplastic Agents, ImmunologicalBI 836826CD37 protein, humanTetraspanins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.