ArticleEye (London, England)2019
Serous retinal detachment in preeclampsia and malignant hypertension.
Article in Eye (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- The Application of Optical Coherence Tomography Angiography in Systemic Hypertension: A Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Adaptive Optics RTX1 Imaging for Early Detection of Retinal Vascular Remodeling in Hypertensive Retinopathy: A Review.Journal of clinical medicine · 2026Review
- Exudative retinal detachment and hypertensive choroidopathy in a patient with suspected HELLP syndrome: a case report.BMC ophthalmology · 2025Article
- Clinical implications of a history of pre-eclampsia in women with type two diabetes mellitus.Diabetic medicine : a journal of the British Diabetic Association · 2025Article
- The Molecular and Cellular Basis of Physiological Changes in Pregnancy and Its Implications in Neurologic and Ophthalmic Pathologies.International journal of molecular sciences · 2025Review
- Noninvasive early prediction of preeclampsia in pregnancy using retinal vascular features.NPJ digital medicine · 2025Article
- Instrumenting Carotid Sonography Biomarkers and Polygenic Risk Score As a Novel Screening Approach for Retinal Detachment.Translational vision science & technology · 2025Article
- Hypertensive Choroidopathy With Bilateral Serous Retinal Detachment as the Presenting Finding in Malignant Hypertension.Case reports in ophthalmological medicine · 2025Article
- Preeclampsia and the Retina.Current hypertension reports · 2024Review
- Article
- Quantitative analysis of choroidal morphology in preeclampsia during pregnancy according to retinal change.Scientific reports · 2023Article
- Unilateral hypertensive choroidopathy as a sole manifestation in malignant hypertension: optical coherence tomography angiography findings-case report.BMC ophthalmology · 2023Article
- Article
- Review
- Preeclampsia and eclampsia: the conceptual evolution of a syndrome.American journal of obstetrics and gynecology · 2022Review
- Visual complaints in pregnancy: (pre)eclampsia as a chameleon.GMS ophthalmology cases · 2022Article
- Subretinal Deposits in Pre-eclampsia and Malignant Hypertension: Implications for Age-Related Macular Degeneration.Ophthalmology. Retina · 2021Article
- Acute Hypertensive Retinochoroidopathy Secondary to an Anti-cancer Drug (apatinib): The First Case Report.Frontiers in medicine · 2021Article
- Concurrent analogous organ damage in the brain, eyes, and kidneys in malignant hypertension: reversible encephalopathy, serous retinal detachment, and proteinuria.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Pre-eclampsia associated bilateral serous retinal detachment.BMJ case reports · 2020Article
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5 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo compare and evaluate the characteristics of hypertensive choroidopathy with serous retinal detachment in preeclampsia and malignant hypertension (HTN) and explore choroidal ischemia as a pathogenesis using multimodal imaging.
methodsA retrospective multicenter case series. Medical charts were reviewed. Clinical characteristics and multimodal imaging, including optical coherence tomography (OCT) and OCT angiography (OCTA), were evaluated.
resultsFifty-three eyes of 29 preeclampsia patients and 45 eyes of 24 HTN patients were included. There were no differences in age, follow-up duration, baseline visual acuity, central macular thickness (CMT), or subfoveal choroidal thickness (CT) between the two groups. Blood pressure parameters, including systolic blood pressure, diastolic blood pressure, and pulse rate, were significantly higher in the HTN group. After serous retinal detachment resolved, both CMT (p < 0.001) and CT (p = 0.003) decreased more in the preeclampsia group. Hypertensive retinopathy features, including hemorrhage, exudates, cotton-wool spots, and optic disc edema, were predominantly found in the HTN group (p = 0.001). Final visual acuity was better in the preeclampsia group than in the HTN group (p = 0.048). Poor visual prognostic factors included the presence of retinopathy features (p = 0.005) and retinal detachment in the macula (p = 0.017).
conclusionChoroidal circulation may be affected earlier than retinal circulation by elevated blood pressure, presumably because of anatomical differences and autoregulatory mechanisms in the retinal vasculature. Serous retinal detachment with hypertensive choroidopathy presented with choroidal thickening that decreased after resolution, but the residual flow defects observed in the choriocapillaris on OCTA confirmed the long-hypothesized notion that ischemia is a mechanism underlying hypertensive choroidopathy.
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