Evidence map›Paper›PMID 31088939›Full record

ArticleJournal of neurointerventional surgery2019

Flow diversion beyond the circle of Willis: endovascular aneurysm treatment in peripheral cerebral arteries employing a novel low-profile flow diverting stent.

Stefan Schob, Karl-Titus Hoffmann, Cindy Richter, Pervinder Bhogal, Katharina Köhlert, Uwe Planitzer, Svitlana Ziganshyna, Dirk Lindner, Cordula Scherlach, Ulf Nestler and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurointerventional surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Patient outcomes after treatment of brain aneurysm in small diameter vessels with the silk vista baby flow diverter: A systematic review.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
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  14. A novel intracranial exchange guidewire improves the navigation of various endovascular devices: An in vitro study of challenging situations.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
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  15. Early clinical experience with the p48MW HPC and p64MW HPC flow diverters in the anterior circulation aneurysm using single anti-platelet treatment.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
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  16. The Silk Vista Baby - The UK experience.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
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  17. Pipeline embolization of proximal middle cerebral artery aneurysms: A multicenter cohort study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Stefan SchobDepartment for Neuroradiology, University Hospital Leipzig, Leipzig, Germany.ORCID http://orcid.org/0000-0003-2846-5443
Karl-Titus Hoffmann *Department for Neuroradiology, University Hospital Leipzig, Leipzig, Germany.
Cindy RichterDepartment for Neuroradiology, University Hospital Leipzig, Leipzig, Germany.
Pervinder BhogalDepartment of Interventional Neuroradiology, Royal London Hospital, London, UK.ORCID http://orcid.org/0000-0002-5514-5237
Katharina KöhlertDepartment for Neurosurgery, University Hospital Leipzig, Leipzig, Saxony, Germany.
Uwe PlanitzerDepartment for Neurosurgery, University Hospital Leipzig, Leipzig, Saxony, Germany.
Svitlana ZiganshynaDepartment for Anesthesiology, University Hospital Leipzig, Leipzig, Germany.
Dirk LindnerDepartment for Neurosurgery, University Hospital Leipzig, Leipzig, Saxony, Germany.
Cordula ScherlachDepartment for Neuroradiology, University Hospital Leipzig, Leipzig, Germany.
Ulf NestlerDepartment for Neurosurgery, University Hospital Leipzig, Leipzig, Saxony, Germany.
Jürgen Meixensberger *Department for Neurosurgery, University Hospital Leipzig, Leipzig, Saxony, Germany.
Ulf Quäschling *Department for Neuroradiology, University Hospital Leipzig, Leipzig, Germany.
University Hospital Leipzig · DERoyal London Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFlow diversion (FD) has emerged as superior minimally invasive therapy for cerebral aneurysms. However, aneurysms of small peripheral vessel segments have not yet been adequately treatable. More specifically, currently established devices necessitate large microcatheters which impede atraumatic maneuvering. The Silk Vista Baby (SVB), a novel flow diverter, offers the as yet unique feature of deliverability via a 0.017 inch microcatheter. This study reports our first experience with the SVB in challenging intracranial vessels employing a vessel-specific tailored microcatheter strategy. MATERIALS AND

methods25 patients (27 aneurysms) were prospectively included. A total of 30 SVBs were employed, predominantly targeting demanding aneurysms of the anterior communicating artery complex. The efficacy of the FD was assessed using two-dimensional vector-based perfusion and conventional digital subtraction angiography (DSA) after implantation and at the first follow-up at 3 months. The first follow-up was available in 22 patients.

resultsAll devices were implanted without technical or clinical complications. Eleven treatments were performed using the recommended Headway 17. In 14 interventions the even more maneuverable Excelsior SL10 was used, which was previously tried and tested for safety 'in vitro' as an alternative delivery system. Aneurysmal influx was strongly reduced after implantation. All parent vessels remained patent. 17/27 aneurysms were completely occluded at first follow-up (∼2.7 months), 6/27 aneurysms showed decreased influx or delayed washout and one remained unchanged. In three cases follow-up DSAs are remaining.

conclusionsSVB provides enhanced controllability in vulnerable segments beyond the circle of Willis. Smaller variants (2.25 mm and 2.75 mm) can safely be implanted via the superiorly navigable Excelsior SL10. Hence, the SVB represents the next evolutionary step in minimally invasive treatment of cerebral aneurysms.

Indexed as

Self Expandable Metallic StentsAdolescentAdultAgedAngiography, Digital SubtractionBlood Vessel Prosthesis ImplantationCircle of WillisEndovascular ProceduresFemaleHumansIntracranial AneurysmMaleMiddle AgedProspective StudiesRetrospective StudiesTreatment Outcomedistal aneurysmsflow diversionlow profile flow divertersilk vista babysmall cerebral vessels

Identifiers

PMID31088939
PMCPMC6902074
OpenAlexW2945208798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.