Evidence map›Paper›PMID 31088910›Full record

ArticleThe Journal of biological chemistry2019

Toll family members bind multiple Spätzle proteins and activate antimicrobial peptide gene expression in

Munmun Chowdhury, Chun-Feng Li, Zhen He, Yuzhen Lu, Xu-Sheng Liu, Yu-Feng Wang, Y Tony Ip, Michael R Strand, Xiao-Qiang Yu

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
  2. Article
  3. Crosstalk BetweenInsects · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. GαCell communication and signaling : CCS · 2025
    Article
  9. Article
  10. Article
  11. Activation ofInsects · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Similarly toInsects · 2024
    Article
  16. Article
  17. A myeloid differentiation-like protein in partnership with Toll5 from the pest insectProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. A New Overview of Sex Bias in Fungal Infections.Journal of fungi (Basel, Switzerland) · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Munmun ChowdhuryFrom the Division of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri 64110.
Chun-Feng LiFrom the Division of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri 64110.
Zhen HeFrom the Division of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri 64110.
Yuzhen Luthe Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology and School of Life Sciences, South China Normal University, Guangzhou 510631, China.
Xu-Sheng Liuthe School of Life Sciences, Central China Normal University, Wuhan 430079, China.
Yu-Feng Wangthe School of Life Sciences, Central China Normal University, Wuhan 430079, China.
Y Tony Ipthe Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605.
Michael R Strandthe Department of Entomology, University of Georgia, Athens, Georgia 30602, and mrstrand@uga.edu.
Xiao-Qiang YuFrom the Division of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri 64110, Yux@umkc.edu.ORCID 0000-0003-1419-9009
Central China Normal University · CNSouth China Normal University · CNSouthwest University · CNUniversity of Georgia · USUniversity of Massachusetts Chan Medical School · USUniversity of Missouri–Kansas City · US

Funding

Genetic analysis of damage-induced intestinal stem cell division in DrosophilaR01DK083450 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI IP, Y. TONY · 2010 to 2024
$4.7M
Homeostatic signaling in the Drosophila intestineR01GM107457 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI IP, Y. TONY · 2015 to 2018
$1.3M
NIDDK NIH HHS R01 DK083450NIGMS NIH HHS R01 GM107457
6 · The paper itself

Abstract

The Toll signaling pathway in

Indexed as

Gene Expression RegulationAnimalsAntimicrobial Cationic PeptidesBacteriaBacterial InfectionsDrosophila melanogasterDrosophila ProteinsFemaleMalePromoter Regions, GeneticSignal TransductionToll-Like ReceptorsAntimicrobial Cationic PeptidesDrosophila ProteinsDRS protein, Drosophilaspz protein, DrosophilaToll-Like Receptorsantimicrobial peptide (AMP)cytokine responsegene regulationinsect immunitysex-specific differencesignal transductionSpätzletoll receptor

Identifiers

PMID31088910
PMCPMC6664172
OpenAlexW2945987049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.