ArticleCancer research2019
Metabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway.
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Article in Cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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0cells of the map it votes in
69citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed, 113 citations in OpenAlex.
- MYCN-driven metabolic remodelling of the tumour microenvironment in neuroblastoma: implications for stromal biology and CAF heterogeneity.Cancer metastasis reviews · 2026Review
- Long noncoding RNA MNX1-AS1 mediated regulation of one-carbon metabolism by preventing CACYBP degradation to promote lung cancer progression.Cell death and differentiation · 2026Article
- The integrated stress response in cancer: mechanisms of tumor adaptation and therapeutic targeting.Biochemical Society transactions · 2026Review
- Targeting mitochondrial homeostasis as a cancer treatment strategy: current status and future prospects.Molecular cancer · 2026Review
- Construction of a linezolid-resistant strain of methicillin-susceptibleFrontiers in cellular and infection microbiology · 2026Article
- ZNF526 drives tumor growth by enhancing SHMT1-dependent serine metabolism and antioxidant capability in TNBC.Molecular cancer · 2025Article
- Review
- A computational model elucidates the effects of oncogene-induced expression alterations on the energy metabolism of neuroblastoma.Scientific reports · 2025Article
- A Novel Approach for Cisplatin-Resistant Esophageal Squamous Cell Carcinoma via Amino Acid Transporter LAT1 Inhibition.Cancer medicine · 2025Article
- DKC1-mediated pseudouridylation of rRNA targets hnRNP A1 to sustain IRES-dependent translation and ATF4-driven metabolic adaptation.Science advances · 2025Article
- Targeting Pathways in Neuroblastoma: Advances in Treatment Strategies and Clinical Outcomes.International journal of molecular sciences · 2025Review
- MYC-dependent upregulation of the de novo serine and glycine synthesis pathway is a targetable metabolic vulnerability in group 3 medulloblastoma.Neuro-oncology · 2025Article
- Molecular regulation and therapeutic targeting ofFrontiers in cell and developmental biology · 2025Review
- Targeting tumor angiogenesis and metabolism: a new perspective in pediatric thoracic tumor therapy.Frontiers in cell and developmental biology · 2025Review
- Defining neuroblastoma: From origin to precision medicine.Neuro-oncology · 2024Review
- MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development.Cancer research · 2024Article
- Control of epigenomic landscape and development of fetal male germ cells through L-serine metabolism.iScience · 2024Article
- Joint metabolomics and transcriptomics analysis systematically reveal the impact of MYCN in neuroblastoma.Scientific reports · 2024Article
- Integrative single-cell and bulk transcriptomes analyses reveals heterogeneity of serine-glycine-one-carbon metabolism with distinct prognoses and therapeutic vulnerabilities in HNSCC.International journal of oral science · 2024Article
- Role of dietary nutrients and metabolism in colorectal cancer.Asia Pacific journal of clinical nutrition · 2024Review
9 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
16 authors at 4 institutions in 3 countries.
Yingfeng Xia *Institute of Neural Regeneration and Repair and Department of Neurology, The First Hospital of Yichang, Three Gorges University College of Medicine, Yichang, China.
Bingwei Ye *Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia.
Jane Ding *Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia.
Yajie YuInstitute of Neural Regeneration and Repair and Department of Neurology, The First Hospital of Yichang, Three Gorges University College of Medicine, Yichang, China.
Ahmet AlptekinGeorgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia.
Muthusamy ThangarajuDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.
Puttur D PrasadDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.
Zhi-Chun DingGeorgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia.
Eun Jeong ParkGeorgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia.
Jeong-Hyeon ChoiNational Marine Bio-Resources and Information Center, National Marine Biodiversity Institute of Korea, Chungchungnam-do, Republic of Korea.
Bei GaoNIH West Coast Metabolomics Center, University of California, Davis, California.
Oliver FiehnNIH West Coast Metabolomics Center, University of California, Davis, California.ORCID https://orcid.org/0000-0002-6261-8928
Chunhong YanGeorgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia.
Zheng DongDepartment of Cell Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, Georgia.
Yunhong ZhaInstitute of Neural Regeneration and Repair and Department of Neurology, The First Hospital of Yichang, Three Gorges University College of Medicine, Yichang, China. hding@augusta.edu yzha7808@ctgu.edu.cn.
Han-Fei DingGeorgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia. hding@augusta.edu yzha7808@ctgu.edu.cn.
Augusta University · USChina Three Gorges University · CNWest Coast University · USMarine Biodiversity Institute of Korea · KR
Funding
RNA epigenetic regulation of cancer metabolismR01CA190429 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HAN-FEI DING · 2014 to 2026
$3.7MNCI NIH HHS R01 CA190429
Abstract
PubMed holds no abstract for this paper.
Indexed as
NeuroblastomaSerineBiosynthetic PathwaysCarbonCell Line, TumorChildGlycineHumansN-Myc Proto-Oncogene ProteinCarbonGlycineMYCN protein, humanN-Myc Proto-Oncogene ProteinSerine
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.