Evidence map›Paper›PMID 31088561›Full record

ArticleBMC public health2019

Prevalence of prescribed benzodiazepine long-term use in the French general population according to sociodemographic and clinical factors: findings from the CONSTANCES cohort.

Guillaume Airagnes, Cédric Lemogne, Adeline Renuy, Marcel Goldberg, Nicolas Hoertel, Yves Roquelaure, Frédéric Limosin, Marie Zins

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

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  10. Long-term benzodiazepine prescriptions in community psychiatry clinics.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024
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  11. [Factors associated with benzodiazepines dependence in insomnia patients].Revista medica del Instituto Mexicano del Seguro Social · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Guillaume AiragnesDepartment of Psychiatry and Addictology, Hôpitaux Universitaires Paris Ouest, AP-HP, Paris, France. guillaume.airagnes@aphp.fr.ORCID http://orcid.org/0000-0002-3494-5083
Cédric LemogneDepartment of Psychiatry and Addictology, Hôpitaux Universitaires Paris Ouest, AP-HP, Paris, France.
Adeline RenuyUMS 011, Population-based Epidemiological Cohorts, Inserm, Villejuif, France.
Marcel GoldbergFaculté de Médecine, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Nicolas HoertelDepartment of Psychiatry and Addictology, Hôpitaux Universitaires Paris Ouest, AP-HP, Paris, France.
Yves RoquelaureUMR 1085, Ester, Irest Inserm, Université d'Angers, Angers, France.
Frédéric LimosinDepartment of Psychiatry and Addictology, Hôpitaux Universitaires Paris Ouest, AP-HP, Paris, France.
Marie ZinsFaculté de Médecine, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Délégation Paris 5 · FRInserm · FR

Funding

Agence Nationale de la Recherche ANR-11-INBS-0002
6 · The paper itself

Abstract

backgroundData are lacking regarding the prevalence of benzodiazepine long-term use in the general population. Our aim was to examine the prevalence of prescribed benzodiazepine long-term use (BLTU) according to sociodemographic and clinical factors in the French general population.

methodsData came from 4686 men and 4849 women included in 2015 in the French population-based CONSTANCES cohort. BLTU was examined using drug reimbursement administrative registries from 2009 to 2015. Analyses were weighted to provide results representative of the French general population covered by the general health insurance scheme. Weighted prevalence of BTLU and weighted Odds Ratios (OR) of having BTLU were computed with their 95% Confidence Interval (95% CI) according to age, education level, occupational status, occupational grade, household income, marital status, alcohol use disorder risk and depressive symptoms. All the analyses were stratified for gender.

resultsWeighted prevalence of BLTU were 2.8%(95% CI:2.3-3.4) and 3.8%(95% CI: 3.3-4.5) in men and women, respectively. Compared to men, women had an increased risk of having benzodiazepine long-term use with OR = 1.34(95% CI = 1.02-1.76). Aging, low education, not being at-work, low occupational grade, low income, being alone and depressive state were associated with increased risks of having BTLU.

conclusionsBLTU is widespread in the French general population, however this issue may particularly concern vulnerable subgroups. These findings may help in raising attention on this public health burden as well as targeting specific at-risk subgroups in preventive intervention.

Indexed as

Time FactorsAdultAgedBenzodiazepinesCohort StudiesDepressionDrug PrescriptionsEmploymentFemaleFranceHumansInsurance, Health, ReimbursementMaleMarital StatusMiddle AgedOdds RatioBenzodiazepinesAdministrative registriesAlcohol useBenzodiazepineDepressionFrench national cohortGeneral populationLong-term useMisusePrevalenceSociodemographic factors

Identifiers

PMID31088561
PMCPMC6518636
OpenAlexW2945365320

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.