Evidence map›Paper›PMID 31088407›Full record

ArticleBMC pediatrics2019

Prenatal alcohol exposure and infant gross motor development: a prospective cohort study.

Delyse Hutchinson, George J Youssef, Clare McCormack, Judy Wilson, Steve Allsop, Jake Najman, Elizabeth Elliott, Lucinda Burns, Sue Jacobs, Ingrid Honan and 6 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  6. Functional Consequences Paternal Preconceptual Alcohol Consumption.Current topics in behavioral neurosciences · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Delyse HutchinsonNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia. delyse.hutchinson@deakin.edu.au.ORCID 0000-0003-3221-7143
George J YoussefFaculty of Health, School of Psychology, Centre for Social and Early Emotional Development, Deakin University, Geelong, Victoria, 3125, Australia.
Clare McCormackNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
Judy WilsonNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
Steve AllsopNational Drug Research Institute, Curtin University, Perth, Australia.
Jake NajmanQueensland Alcohol and Drug Research and Education Centre and Schools of Public Health and Social Science, University of Queensland, Brisbane, Australia.
Elizabeth ElliottDiscipline of Child and Adolescent Health, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Lucinda BurnsNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
Sue JacobsDepartment of Obstetrics, Royal Prince Alfred Hospital, Sydney, Australia.
Ingrid HonanNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
Larissa RossenNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
Hannah FiedlerNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
Samantha TeagueFaculty of Health, School of Psychology, Centre for Social and Early Emotional Development, Deakin University, Geelong, Victoria, 3125, Australia.
Joanne RyanDepartment of Paediatrics, University of Melbourne, Royal Children's Hospital, Melbourne, Australia.
Craig A OlssonFaculty of Health, School of Psychology, Centre for Social and Early Emotional Development, Deakin University, Geelong, Victoria, 3125, Australia.
Richard P MattickNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
UNSW Sydney · AURoyal Children's Hospital · AUDeakin University · AUCurtin University · AURoyal Prince Alfred Hospital · AUThe University of Queensland · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaternal alcohol consumption in pregnancy may have adverse effects on child gross motor (GM) development. There have been few human studies on this topic, particularly ones examining low exposure. This study examined the association between prenatal alcohol exposure (PAE) and infant GM development at 12-months of age.

methodsParticipants were 1324 women recruited from antenatal clinics in Sydney and Perth, Australia. Maternal and paternal alcohol use was assessed in pregnancy via interview; offspring GM development was measured at 12-months with the Bayley Scales of Infant Development (BSID-III).

resultsAny alcohol use in pregnancy was common: 56.1%, of pregnant women drank early in Trimester one (0-6 weeks), however this reduced to 27.9% on average thereafter and at predominantly low levels. However, infant BSID GM scale scores were not found to differ significantly as a function of PAE in the first 6-weeks (low, moderate, binge or heavy PAE), nor with low PAE across pregnancy.

conclusionsWe found no evidence to suggest that low PAE is associated with measurable impairment in infant GM development at 12-months. Further research is needed to examine potential PAE impacts on GM development in heavier exposure groups and through the childhood years when subtle GM deficits may be more detectable.

Indexed as

AdultAlcohol DrinkingAustraliaDatabases, FactualFemaleFetal Alcohol Spectrum DisordersHumansInfant, NewbornMaleMaternal ExposureMotor Skills DisordersPregnancyPrenatal CarePrenatal Exposure Delayed EffectsPrevalencePrognosisAlcoholInfancyMotor SkillsPerinatal

Identifiers

PMID31088407
PMCPMC6515673
OpenAlexW2946715225

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.