ArticleBMC plant biology2019
Transcriptional regulation of Lonicera japonica Thunb. during flower development as revealed by comprehensive analysis of transcription factors.
Article in BMC plant biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- Protective effect of Lonicerae Japonicae Flos extract against doxorubicin-induced myocardial injury in mice and the possible mechanisms.Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- LoniComp: a platform for gene function comparison and analysis between Lonicera japonica and Lonicera macranthoides.BMC genomics · 2025Article
- Callus Culture System fromInternational journal of molecular sciences · 2025Article
- Metabolomics combined with transcriptomics reveals the formation mechanism of different leaf colors ofFrontiers in plant science · 2025Article
- The Mitochondrial Blueprint: Unlocking Secondary Metabolite Production.Metabolites · 2024Review
- Transcriptomic and metabolomic profiling reveals molecular regulatory network involved in flower development and phenotypic changes in two3 Biotech · 2024Article
- GA signaling protein LsRGL1 interacts with the abscisic acid signaling-related geneHorticulture research · 2023Article
- Transcriptome analysis of critical genes related to flowering in Mikania micrantha at different altitudes provides insights for a potential control.BMC genomics · 2023Article
- De novo transcriptome assembly and analysis of gene expression in different tissues of moth bean (Vigna aconitifolia) (Jacq.) Marechal.BMC plant biology · 2022Article
- Transcriptomic analysis unravels the molecular response ofFrontiers in plant science · 2022Article
- Transcriptome Meta-Analysis Associated Targeting Hub Genes and Pathways of Drought and Salt Stress Responses in Cotton (Frontiers in plant science · 2022Article
- Whole-Transcriptome Analysis Reveals Autophagy Is Involved in Early Senescence ofFrontiers in plant science · 2022Article
- Systematic review of Lonicerae Japonicae Flos: A significant food and traditional Chinese medicine.Frontiers in pharmacology · 2022Review
- Genetic Architecture Underlying the Metabolites of Chlorogenic Acid Biosynthesis inInternational journal of molecular sciences · 2021Article
- Anti-inflammatory effects ofInternational journal of medical sciences · 2021Article
- An Integrative Analysis of Transcriptome, Proteome and Hormones Reveals Key Differentially Expressed Genes and Metabolic Pathways Involved in Flower Development in Loquat.International journal of molecular sciences · 2020Article
- Comparative transcriptomics analysis revealing flower trichome development during flower development in two Lonicera japonica Thunb. cultivars using RNA-seq.BMC plant biology · 2020Article
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8 authors at 2 institutions in 1 country.
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Abstract
backgroundLonicera japonica Thunb. flower has been used for the treatment of various diseases for a long time and attracted many studies on its potential effects. Transcription factors (TFs) regulate extensive biological processes during plant development. As the restricted reports of L. japonica on TFs, our work was carried out to better understand the TFs' regulatory roles under different developmental stages in L. japonica.
resultsIn this study, 1316 TFs belonging to 52 families were identified from the transcriptomic data, and corresponding expression profiles during the L. japonica flower development were comprehensively analyzed. 917 (69.68%) TFs were differentially expressed. TFs in bHLH, ERF, MYB, bZIP, and NAC families exhibited obviously altered expression during flower growth. Based on the analysis of differentially expressed TFs (DETFs), TFs in MYB, WRKY, NAC and LSD families that involved in phenylpropanoids biosynthesis, senescence processes and antioxidant activity were detected. The expression of MYB114 exhibited a positive correlation with the contents of luteoloside; Positive correlation was observed among the expression of MYC12, chalcone synthase (CHS) and flavonol synthase (FLS), while negative correlation was observed between the expression of MYB44 and the synthases; The expression of LSD1 was highly correlated with the expression of SOD and the total antioxidant capacity, while the expression of LOL1 and LOL2 exhibited a negative correlation with them; Many TFs in NAC and WRKY families may be potentially involved in the senescence process regulated by hormones and reactive oxygen species (ROS). The expression of NAC19, NAC29, and NAC53 exhibited a positive correlation with the contents of ABA and H
conclusionsOur study provided a comprehensive characterization of the expression profiles of TFs during the developmental stages of L. japonica. In addition, we detected the key TFs that may play significant roles in controlling active components biosynthesis, antioxidant activity and flower senescence in L. japonica, thereby providing valuable insights into the molecular networks underlying L. japonica flower development.
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