Evidence map›Paper›PMID 31088358›Full record

ArticleBMC cardiovascular disorders2019

Clinical study of chlamydia pneumoniae infection in patients with coronary heart disease.

Lei Xue, Yan-Hong Liang, Yuan-Yuan Gao, Xiao-Juan Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Atypical pneumonia (Review).Experimental and therapeutic medicine · 2024
    Review
  3. Chlamydiosis in Animals.Animals : an open access journal from MDPI · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lei XueGeneral Department, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gong-Ti South Road, Beijing, 100020, China.
Yan-Hong LiangGeneral Department, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gong-Ti South Road, Beijing, 100020, China.
Yuan-Yuan GaoGeneral Department, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gong-Ti South Road, Beijing, 100020, China.
Xiao-Juan WangGeneral Department, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gong-Ti South Road, Beijing, 100020, China. wangxiaojuan72@21cn.com.ORCID 0000-0003-4556-1111
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to investigate the chlamydia pneumoniae infection (PC) in patients with coronary heart disease.

methodsA total of 92 patients with coronary heart disease, who were treated with percutaneous coronary intervention (PCI), were selected as the case group. In addition, 50 healthy people were enrolled as the control group. The incidences of CP infection and serum Chlamydia pneumoniae IgA antibody (CP-IgA), high sensitive C-reactive protein (hs-CRP), and interleukin-6 (IL-6) were compared in these two groups. The classification of coronary artery lesion, the incidence of perioperative cardiovascular events, and adverse prognosis events within six months after procedure were compared.

resultsThe incidence of CP infection in the case group was higher (42.4% vs. 0%, P < 0.05). Furthermore, 17 patients were at grade I, 39 patients were at grade II, and 36 patients were at grade III. The incidences for these three kinds of patients were 17.6, 30.8, and 66.7%. The incidence of CP infection at grade III was higher than that of grade I or II (P < 0.05). Serum CP-IgA, hs-CRP and IL-6 levels increased with the severity of the coronary artery disease (P < 0.05), and the serum hs-CRP and IL-6 levels of patients with perioperative cardiovascular events were higher (P < 0.05). Moreover, the serum CP-IgA levels of the patients with adverse prognosis events were also higher (P < 0.05).

conclusionsPatients with coronary heart disease have a high CP infection rate. The degree of infection is relevant to the severity of the coronary artery lesions and postoperative prognosis of patients, suggesting that CP infection may be an important factor affecting the incidence and prognosis of coronary heart disease.

Indexed as

Antibodies, BacterialBeijingBiomarkersCase-Control StudiesChlamydophila InfectionsChlamydophila pneumoniaeCoronary DiseaseC-Reactive ProteinFemaleHumansImmunoglobulin AIncidenceInterleukin-6MaleMiddle AgedPercutaneous Coronary InterventionAntibodies, BacterialBiomarkersC-Reactive ProteinIL6 protein, humanImmunoglobulin AInterleukin-6Chlamydia pneumoniaeCoronary heart diseaseInfectionInflammatory factorPrognosis

Identifiers

PMID31088358
PMCPMC6518631
OpenAlexW2947494961

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.