Evidence map›Paper›PMID 31088290›Full record

ArticleAntioxidants & redox signaling2019

Suppression of Cardiac Autophagy by Hyperinsulinemia in Insulin Receptor-Deficient Hearts Is Mediated by Insulin-Like Growth Factor Receptor Signaling.

Karla Maria Pires, Natalia S Torres, Marcio Buffolo, River Gunville, Christin Schaaf, Kathryn Davis, Craig H Selzman, Roberta A Gottlieb, Sihem Boudina

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Antioxidants & redox signaling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Insulin signaling in the heart.American journal of physiology. Endocrinology and metabolism · 2021
    Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Karla Maria Pires1 Department of Nutrition and Integrative Physiology, Program in Molecular Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
Natalia S Torres2 Nora Eccles Harrison Cardiovascular Research and Training Institute, Salt Lake City, Utah.
Marcio Buffolo1 Department of Nutrition and Integrative Physiology, Program in Molecular Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
River Gunville1 Department of Nutrition and Integrative Physiology, Program in Molecular Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
Christin Schaaf3 Division of Cardiothoracic Surgery, University of Utah School of Medicine, Salt Lake City, Utah.
Kathryn Davis2 Nora Eccles Harrison Cardiovascular Research and Training Institute, Salt Lake City, Utah.
Craig H Selzman3 Division of Cardiothoracic Surgery, University of Utah School of Medicine, Salt Lake City, Utah.
Roberta A Gottlieb4 The Smidt Heart Institute, Cedars-Sinai Heart Institute, Los Angeles, California.
Sihem Boudina1 Department of Nutrition and Integrative Physiology, Program in Molecular Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
Harrison Medical Center · USUniversity of Utah · US

Funding

WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
Protein Chemistry and ProteomicsP01HL112730 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI VAN EYK, JENNIFER E · 2013 to 2017
$12.0M
White Adipose Tissue Physiology, Mitochondrial Function and AdiponectinR01DK099110 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI PHILIPP E SCHERER · 2013 to 2026
$6.7M
Mitochondrial Turnover in the Human HeartR01HL132075 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI GOTTLIEB, ROBERTA A., VAN EYK, JENNIFER E · 2017 to 2020
$2.1M
Mechanisms of Myocardial RecoveryR01HL089592 · NHLBI · UNIVERSITY OF UTAH · PI SELZMAN, CRAIG HAROLD · 2009 to 2013
$1.8M
Post-Developmental Adipocyte Autophagy in Control of Insulin-Glucose HomeostasisR01DK100826 · NIDDK · UNIVERSITY OF UTAH · PI BOUDINA, SIHEM · 2013 to 2017
$1.6M
Novel pathways for fat burning that protects from high fat diet-induced metabolicR01DK098646 · NIDDK · UNIVERSITY OF UTAH · PI BOUDINA, SIHEM · 2013 to 2017
$1.6M
Native American Summer Research Internship in Maternal/Child HealthR25MD006781 · NIMHD · UNIVERSITY OF UTAH · PI BYINGTON, CARRIE L. · 2011 to 2015
$1.0M
NHLBI NIH HHS P01 HL112730NHLBI NIH HHS R01 HL089592NHLBI NIH HHS R01 HL132075NIDDK NIH HHS P30 DK020579NIDDK NIH HHS R01 DK098646NIDDK NIH HHS R01 DK099110NIDDK NIH HHS R01 DK100826NIMHD NIH HHS R25 MD006781
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AutophagySignal TransductionAnimalsCells, CulturedEchocardiographyHeartHyperinsulinismInsulinMaleMiceMice, Inbred C57BLReceptor, IGF Type 1Receptor, InsulinInsulinReceptor, IGF Type 1Receptor, Insulinautophagycardiomyocytescontractile functionhyperinsulinemiaIGF-1 receptorsinsulin

Identifiers

PMID31088290
PMCPMC6653796
OpenAlexW2946480845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.