ArticleJournal of the Royal Society, Interface2019
Evolution of simple multicellular life cycles in dynamic environments.
Article in Journal of the Royal Society, Interface, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 31 citations in OpenAlex.
- The embryo game uncovers hidden cell behaviours.Nature communications · 2026Article
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- Steady-State and Dynamical Behavior of a PDE Model of Multilevel Selection with Pairwise Group-Level Competition.Bulletin of mathematical biology · 2025Article
- Evolutionary dynamics of nascent multicellular lineages.Proceedings. Biological sciences · 2025Article
- Cell size and selection for stress-induced cell fusion in unicellular eukaryotes.PLoS computational biology · 2025Article
- Polyphenols in bee products and prevention of cell senescence.BioMedicine · 2024Review
- Alternating selection for dispersal and multicellularity favors regulated life cycles.Current biology : CB · 2023Article
- Article
- The possible modes of microbial reproduction are fundamentally restricted by distribution of mass between parent and offspring.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Evolution of reproductive strategies in incipient multicellularity.Journal of the Royal Society, Interface · 2022Article
- Cellular Senescence and Ageing: Mechanisms and Interventions.Frontiers in aging · 2022Review
- Multilevel selection favors fragmentation modes that maintain cooperative interactions in multispecies communities.PLoS computational biology · 2021Article
- Evolution of multicellular life cycles under costly fragmentation.PLoS computational biology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mode of reproduction is a critical characteristic of any species, as it has a strong effect on its evolution. As any other trait, the reproduction mode is subject to natural selection and may adapt to the environment. When the environment varies over time, different reproduction modes could be optimal at different times. The natural response to a dynamic environment seems to be bet hedging, where multiple reproductive strategies are stochastically executed. Here, we develop a framework for the evolution of simple multicellular life cycles in a dynamic environment. We use a matrix population model of undifferentiated multicellular groups undergoing fragmentation and ask which mode maximizes the population growth rate. Counterintuitively, we find that natural selection in dynamic environments generally tends to promote deterministic, not stochastic, reproduction modes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.