Evidence map›Paper›PMID 31088235›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

Memory impairment in spontaneously hypertensive rats is associated with hippocampal hypoperfusion and hippocampal vascular dysfunction.

Abbie C Johnson, Justin E Miller, Marilyn J Cipolla

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 54 citations in OpenAlex.

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  20. Treatment with apocynin selectively restores hippocampal arteriole function and seizure-induced hyperemia in a model of preeclampsia.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Abbie C JohnsonDepartment of Neurological Sciences, University of Vermont Larner College of Medicine, Burlington, VT, USA.ORCID 0000-0002-7242-1715
Justin E MillerDepartment of Neurological Sciences, University of Vermont Larner College of Medicine, Burlington, VT, USA.
Marilyn J CipollaDepartment of Neurological Sciences, University of Vermont Larner College of Medicine, Burlington, VT, USA.
University of Vermont · US

Funding

Targeting Pial Collaterals for Acute Stroke TreatmentR01NS093289 · NINDS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI Marilyn J Cipolla · 2015 to 2026
$3.9M
Hippocampal arteriole remodeling and brain injury in preeclampsia and eclampsiaR01NS108455 · NINDS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI CIPOLLA, MARILYN J · 2018 to 2022
$1.9M
NINDS NIH HHS R01 NS093289NINDS NIH HHS R01 NS108455
6 · The paper itself

Abstract

We investigated the effect of chronic hypertension on hippocampal arterioles (HippAs) and hippocampal perfusion as underlying mechanisms of memory impairment, and how large artery stiffness relates to HippA remodeling. Using male spontaneously hypertensive rats (SHR) and normotensive Wistar rats (

Indexed as

AnimalsAorta, ThoracicArteriolesBehavior, AnimalBiomechanical PhenomenaCerebrovascular CirculationChronic DiseaseDisease Models, AnimalElastinHippocampusHypertensionMaleMemory DisordersRats, Inbred SHRRats, WistarElastinCerebrovascular dysfunctionchronic hypertensionhippocampal blood flowhippocampal hypoperfusionimpaired memory function

Identifiers

PMID31088235
PMCPMC7168795
OpenAlexW2945929351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.