Evidence map›Paper›PMID 31087220›Full record

ArticleThe journal of physiological sciences : JPS2019

Overexpression of the HCN2 channel increases the arrhythmogenicity induced by hypokalemia.

Kensuke Oshita, Yuko Kozasa, Yasuaki Nakagawa, Yoshihiro Kuwabara, Koichiro Kuwahara, Taku Nakagawa, Noriyuki Nakashima, Teruyuki Hiraki, Makoto Takano

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of physiological sciences : JPS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review: HCN Channels in the Heart.Current cardiology reviews · 2022
    Review
  5. Review
  6. Article
  7. Article
  8. Cardiac and neuronal HCN channelopathies.Pflugers Archiv : European journal of physiology · 2020
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kensuke OshitaDepartment of Physiology, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan.
Yuko KozasaDepartment of Physiology, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan.
Yasuaki NakagawaDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yoshihiro KuwabaraDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Koichiro KuwaharaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Taku NakagawaDepartment of Physiology, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan.
Noriyuki NakashimaDepartment of Physiology, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan.
Teruyuki HirakiDepartment of Anesthesiology, Kurume University School of Medicine, Kurume, Japan.
Makoto TakanoDepartment of Physiology, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan. takanom@med.kurume-u.ac.jp.
Kurume University · JPKyoto University · JPShinshu University · JP

Funding

Japan Society for the Promotion of Science 16H05124
6 · The paper itself

Abstract

Hypokalemia, an abnormally low level of potassium (K

Indexed as

AnimalsArrhythmias, CardiacHeart FailureHeart VentriclesHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsHypokalemiaMembrane PotentialsMiceMice, Inbred C57BLMice, TransgenicMyocytes, CardiacPotassiumPotassium ChannelsHcn2 protein, mouseHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsPotassiumPotassium ChannelsArrhythmiaHCN2Heart failureHypokalemia

Identifiers

PMID31087220
PMCPMC6583697
OpenAlexW2945385546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.