Evidence map›Paper›PMID 31087162›Full record

ArticleActa diabetologica2019

Temporal trends without seasonal effects on gestational diabetes incidence relate to reductions in indices of insulin secretion: the Cambridge Baby Growth Study.

Clive J Petry, Benjamin G Fisher, Ken K Ong, Ieuan A Hughes, Carlo L Acerini, David B Dunger

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta diabetologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  3. Climate factors and gestational diabetes mellitus risk - a systematic review.Environmental health : a global access science source · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Clive J PetryDepartment of Paediatrics, University of Cambridge, Box 116, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK. cjp1002@cam.ac.uk.ORCID http://orcid.org/0000-0002-6642-9825
Benjamin G FisherDepartment of Paediatrics, University of Cambridge, Box 116, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK.ORCID http://orcid.org/0000-0001-5497-9689
Ken K OngDepartment of Paediatrics, University of Cambridge, Box 116, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK.ORCID http://orcid.org/0000-0003-4689-7530
Ieuan A HughesDepartment of Paediatrics, University of Cambridge, Box 116, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK.ORCID http://orcid.org/0000-0002-8787-1575
Carlo L AceriniDepartment of Paediatrics, University of Cambridge, Box 116, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK.ORCID http://orcid.org/0000-0003-2121-5871
David B DungerDepartment of Paediatrics, University of Cambridge, Box 116, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK.ORCID http://orcid.org/0000-0002-2566-9304
University of Cambridge · GBMRC Laboratory of Molecular Biology · GB

Funding

Fifth Framework Programme QLK4-1999-01422Medical Research Council 7500001180Medical Research Council G0500733Medical Research Council G0600717Medical Research Council G1001995Medical Research Council MC_UU_12015/2Mothercare Charitable Foundation RG54608Newlife - The Charity for Disabled Children 07/20Wellcome TrustWorld Cancer Research Fund International 2004/03
6 · The paper itself

Abstract

aimsThe incidence of gestational diabetes has been reported to have risen over the first decade of this century. Some studies have also found it to vary with seasons of the year. We investigated temporal and seasonal trends on gestational diabetes incidence in a single-centre cohort study from Cambridge, UK, and attempted to explain trends using associated risk factors.

methodsUsing a cosinor model, we tested both temporal and seasonal trends in gestational diabetes incidence in 1074 women recruited to the Cambridge Baby Growth Study in 2001-2009 who underwent oral glucose tolerance tests around week 28 of pregnancy.

resultsThere was a temporal increase in gestational diabetes incidence over the course of recruitment to this study [0.014 (0.005, 0.022) proportional increase per year, p = 2.1 × 10

conclusionsIn this cohort, there were temporal, but not seasonal, increases in gestational diabetes incidence between the years 2001 and 2009, which appeared to be related more to reductions in insulin secretion than sensitivity. Possible mediators of this link include confounding factors related to deprivation.

Indexed as

AdultBlood GlucoseCohort StudiesDiabetes, GestationalFemaleGlucose Tolerance TestHealth Status IndicatorsHumansIncidenceInsulinInsulin ResistanceInsulin SecretionLongitudinal StudiesPregnancyRisk FactorsSeasonsBlood GlucoseInsulinCosinorDeprivationInsulin sensitivityPregnancy

Identifiers

PMID31087162
PMCPMC6746879
OpenAlexW2917752962

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.