ArticleNeurology(R) neuroimmunology & neuroinflammation2019
α4-integrin deficiency in B cells does not affect disease in a T-cell-mediated EAE disease model.
Erratum issuedOpen access · goldAbstract read
In one paragraph
Article in Neurology(R) neuroimmunology & neuroinflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Enhanced antibody responses in CD19-Cre mice.Scientific reports · 2025Article
- Distinctive transcriptomic and epigenomic signatures of bone marrow-derived myeloid cells and microglia in CNS autoimmunity.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- B cells in central nervous system disease: diversity, locations and pathophysiology.Nature reviews. Immunology · 2022Review
- Breaching Brain Barriers: B Cell Migration in Multiple Sclerosis.Biomolecules · 2022Review
- Skin-Homing Regulatory B Cells Required for Suppression of Cutaneous Inflammation.The Journal of investigative dermatology · 2021Article
- Effects of Natalizumab Therapy on Intrathecal Immunoglobulin G Production Indicate Targeting of Plasmablasts.Neurology(R) neuroimmunology & neuroinflammation · 2021Article
- CD11cProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Article
- Erratum: α4-integrin deficiency in B cells does not affect disease in a T-cell-mediated EAE disease model.Neurology(R) neuroimmunology & neuroinflammation · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 2 institutions in 1 country.
Rehana Z HussainDepartment of Neurology and Neurotherapeutics (R.Z.H., P.C.C., W.A.M.-L., R.D., V.G., D.T.O., O.S.) and Department of Pathology (E.H.), University of Texas Southwestern Medical Center, Dallas; Department of Pathology and Genomic Medicine (T.N.E.), Houston Methodist Hospital; Neurology Section (O.S.), VA North Texas Health Care System, Medical Service; and Department of Neurology (O.S.), Klinikum Rechts der Isar, Technische Universität München, Germany.
Petra D CravensDepartment of Neurology and Neurotherapeutics (R.Z.H., P.C.C., W.A.M.-L., R.D., V.G., D.T.O., O.S.) and Department of Pathology (E.H.), University of Texas Southwestern Medical Center, Dallas; Department of Pathology and Genomic Medicine (T.N.E.), Houston Methodist Hospital; Neurology Section (O.S.), VA North Texas Health Care System, Medical Service; and Department of Neurology (O.S.), Klinikum Rechts der Isar, Technische Universität München, Germany.
William A Miller-LittleDepartment of Neurology and Neurotherapeutics (R.Z.H., P.C.C., W.A.M.-L., R.D., V.G., D.T.O., O.S.) and Department of Pathology (E.H.), University of Texas Southwestern Medical Center, Dallas; Department of Pathology and Genomic Medicine (T.N.E.), Houston Methodist Hospital; Neurology Section (O.S.), VA North Texas Health Care System, Medical Service; and Department of Neurology (O.S.), Klinikum Rechts der Isar, Technische Universität München, Germany.
Richard DoelgerDepartment of Neurology and Neurotherapeutics (R.Z.H., P.C.C., W.A.M.-L., R.D., V.G., D.T.O., O.S.) and Department of Pathology (E.H.), University of Texas Southwestern Medical Center, Dallas; Department of Pathology and Genomic Medicine (T.N.E.), Houston Methodist Hospital; Neurology Section (O.S.), VA North Texas Health Care System, Medical Service; and Department of Neurology (O.S.), Klinikum Rechts der Isar, Technische Universität München, Germany.
Valerie GranadosDepartment of Neurology and Neurotherapeutics (R.Z.H., P.C.C., W.A.M.-L., R.D., V.G., D.T.O., O.S.) and Department of Pathology (E.H.), University of Texas Southwestern Medical Center, Dallas; Department of Pathology and Genomic Medicine (T.N.E.), Houston Methodist Hospital; Neurology Section (O.S.), VA North Texas Health Care System, Medical Service; and Department of Neurology (O.S.), Klinikum Rechts der Isar, Technische Universität München, Germany.
Emily HerndonDepartment of Neurology and Neurotherapeutics (R.Z.H., P.C.C., W.A.M.-L., R.D., V.G., D.T.O., O.S.) and Department of Pathology (E.H.), University of Texas Southwestern Medical Center, Dallas; Department of Pathology and Genomic Medicine (T.N.E.), Houston Methodist Hospital; Neurology Section (O.S.), VA North Texas Health Care System, Medical Service; and Department of Neurology (O.S.), Klinikum Rechts der Isar, Technische Universität München, Germany.
Darin T OkudaDepartment of Neurology and Neurotherapeutics (R.Z.H., P.C.C., W.A.M.-L., R.D., V.G., D.T.O., O.S.) and Department of Pathology (E.H.), University of Texas Southwestern Medical Center, Dallas; Department of Pathology and Genomic Medicine (T.N.E.), Houston Methodist Hospital; Neurology Section (O.S.), VA North Texas Health Care System, Medical Service; and Department of Neurology (O.S.), Klinikum Rechts der Isar, Technische Universität München, Germany.
Todd N EagarDepartment of Neurology and Neurotherapeutics (R.Z.H., P.C.C., W.A.M.-L., R.D., V.G., D.T.O., O.S.) and Department of Pathology (E.H.), University of Texas Southwestern Medical Center, Dallas; Department of Pathology and Genomic Medicine (T.N.E.), Houston Methodist Hospital; Neurology Section (O.S.), VA North Texas Health Care System, Medical Service; and Department of Neurology (O.S.), Klinikum Rechts der Isar, Technische Universität München, Germany.
Olaf StüveDepartment of Neurology and Neurotherapeutics (R.Z.H., P.C.C., W.A.M.-L., R.D., V.G., D.T.O., O.S.) and Department of Pathology (E.H.), University of Texas Southwestern Medical Center, Dallas; Department of Pathology and Genomic Medicine (T.N.E.), Houston Methodist Hospital; Neurology Section (O.S.), VA North Texas Health Care System, Medical Service; and Department of Neurology (O.S.), Klinikum Rechts der Isar, Technische Universität München, Germany.
VA North Texas Health Care System · USMethodist Hospital · US
Funding
Determining the compartmental role of B cell subsets during CNS autoimmunityI01BX001674 · VA · VA NORTH TEXAS HEALTH CARE SYSTEM · PI STUVE, OLAF · 2013 to 2016
–BLRD VA I01 BX001674
Abstract
Objective: The goal of this study was to investigate the role of CD 19 Methods: We generated CD19.Cre Results: A genetic ablation of α4-integrin in CD19 Conclusions: Observations made in CD19.Cre
Indexed as
Adoptive TransferAnimalsAntigens, CD19B-LymphocytesBone MarrowBrainCentral Nervous SystemCytokinesDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalIntegrin alpha4Lymph NodesMiceMice, Inbred C57BLMice, KnockoutSpinal CordAntigens, CD19CytokinesIntegrin alpha4
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.