ArticleBiomedical optics express2019
Long-term Brillouin imaging of live cells with reduced absorption-mediated damage at 660 nm wavelength.
Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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The trial behind it
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Who cites it
42 citing papers in PubMed.
- High-performance Brillouin spectroscopy using VIPA-etalon cascades.Journal of biomedical optics · 2026Article
- Polarization increases nuclear stiffness in macrophages despite reduction in lamin A/C levels.npj biological physics and mechanics · 2026Article
- Macrophages Mediate Mesoscale Brain Mechanical Homeostasis.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- High-Speed Interferometric Scattering Tracking Microscopy of Compartmentalized Lipid Diffusion in Living Cells.Chemphyschem : a European journal of chemical physics and physical chemistry · 2025Article
- Imaging the mechanical properties of a developing embryonic tendon using Brillouin microscopy.Acta biomaterialia · 2025Article
- Full-field Brillouin microscopy based on an imaging Fourier-transform spectrometer.Nature photonics · 2025Article
- Optical characterization of molecular interaction strength in protein condensates.Molecular biology of the cell · 2024Article
- Optical characterization of molecular interaction strength in protein condensates.bioRxiv : the preprint server for biology · 2024Article
- Impact of polarization pulling on optimal spectrometer design for stimulated Brillouin scattering microscopy.APL photonics · 2024Article
- Stimulated Brillouin scattering flow cytometry.Biomedical optics express · 2024Article
- Current state of stimulated Brillouin scattering microscopy for the life sciences.JPhys photonics · 2024Review
- Birefringence-induced phase delay enables Brillouin mechanical imaging in turbid media.Nature communications · 2024Article
- Macrophage mediated mesoscale brain mechanical homeostasis mechanically imaged via optical tweezers and Brillouin microscopybioRxiv : the preprint server for biology · 2024Article
- Network Viscoelasticity from Brillouin Spectroscopy.Biomacromolecules · 2024Article
- Brillouin microscopy.Nature reviews. Methods primers · 2024Article
- Article
- Pulsed stimulated Brillouin microscopy enables high-sensitivity mechanical imaging of live and fragile biological specimens.Nature methods · 2023Article
- High-resolution line-scan Brillouin microscopy for live imaging of mechanical properties during embryo development.Nature methods · 2023Article
- Non-contact and label-free biomechanical imaging: Stimulated Brillouin microscopy and beyond.Frontiers in physics · 2023Article
- Recent advances in optical elastography and emerging opportunities in the basic sciences and translational medicine [Invited].Biomedical optics express · 2023Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
In Brillouin microscopy, absorption-induced photodamage of incident light is the primary limitation on signal-to-noise ratio in many practical scenarios. Here we show that 660 nm may represent an optimal wavelength for Brillouin microscopy as it offers minimal absorption-mediated photodamage at high Brillouin scattering efficiency and the possibility to use a pure and narrow laser line from solid-state lasing medium. We demonstrate that live cells are ~80 times less susceptible to the 660 nm incident light compared to 532 nm light, which overall allows Brillouin imaging of up to more than 30 times higher SNR. We show that this improvement enables Brillouin imaging of live biological samples with improved accuracy, higher speed and/or larger fields of views with denser sampling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.