ArticleThe Pan African medical journal2018
Prevalence of HIV related oral lesions in people living with HIV and on combined antiretroviral therapy: a Nigerian experience.
Article in The Pan African medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 16 citations in OpenAlex.
- Evaluation of oral lesions and dental health in HIV-positive Saudi patients.The Saudi dental journal · 2024Article
- Case Series of HIV-Associated Oral Lesions Across Different Clinical Stages in People Living with HIV.HIV/AIDS (Auckland, N.Z.) · 2024Article
- The Association Between Oral Mucosal Lesions and Oral Health-Related Quality of Life Using the Validated Indonesian Version of OHIP-14 Among People Living with HIV/AIDS.HIV/AIDS (Auckland, N.Z.) · 2024Article
- Case Report: Giant Oral Ulcers Attributed to Cytomegalovirus Infection in a Patient with AIDS.The American journal of tropical medicine and hygiene · 2023Article
- Oral hyperpigmentation as an adverse effect of highly active antiretroviral therapy in HIV patients: A systematic review and pooled prevalence.Journal of clinical and experimental dentistry · 2023Review
- Isolated Epiglottic Manifestations of HIV Infection: Two Cases Reports.Microorganisms · 2022Article
- Evaluation of Sociodemographic Factors and Prevalence of Oral Lesions in People Living with HIV from Cacoal, Rondônia, Amazon Region of Brazil.International journal of environmental research and public health · 2022Article
- Oral health related quality of life among HIV positive patients attending two HIV outpatient clinics in Nigeria - a cross sectional study.African health sciences · 2021Article
- Orofacial lesions associated with long-term highly active antiretroviral therapy among HIV-seropositive adults in Ibadan, Nigeria.The Pan African medical journal · 2021Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
introductionoral lesions comprise significant clinical features of HIV infection and are often indicators of immune suppression. However, the advent of antiretroviral therapy has significantly reduced its prevalence. The aim of this study was to relate the prevalence of oral lesions of HIV to treatment outcome of Combined Antiretroviral Therapy (cART) in a Nigerian HIV adult population.
methodsa cross- sectional study was conducted on 491 People Living with HIV (PLWHIV) on cART from two HIV centres in Lagos state, Nigeria. The EC-clearing house guidelines were employed to categorise oral lesions. Presence or absence of these lesions was reconciled with CD4+ cell count as a measure of efficacy of cART treatment.
resultsa total of 491 PLWHIV on cART were enrolled, 366 (74.5%) were females and 125 (25.5%) were males. Age ranged between 18-80 years, with a mean of 41.2 ± 9.1 years. On examination, 12 (2.4%) patients presented with HIV oral lesions. Oral hyperpigmentation (10, 2.0%) was the most common lesion seen, followed by oral ulcers (2,0.4%). Majority (75%) of the affected patients were on a Lamivudine containing regimen. 7 out of the 12 patients with oral lesions had CD4+ cell count between 200-500 cell/mm
conclusionthe prevalence of oral lesions in HIV patients on cART therapy in Lagos is low. Oral hyperpigmentation and oral ulcers are the most frequent lesions seen. The presence or absence of oral lesions were not associated with CD4+ cell count. Therefore, we conclude that the oral lesions seen in HIV patients on cART may not be a direct manifestation of the disease.
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