Evidence map›Paper›PMID 31086621›Full record

ArticleThe Pan African medical journal2018

Increased urinary sodium excretion is associated with systolic blood pressure in first degree relatives of hypertensive patients in Ibadan, Southwestern Nigeria.

Samuel Ajayi, Adewole Adebiyi, Solomon Kadiri

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The Pan African medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07386535 (Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke Prevention), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07386535 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke Prevention

TypeinterventionalSponsorWashington University School of MedicineRan2026 to 2027Enrolled1,412ConditionsHigh Blood Pressure, StrokeArmsMusic4Health Intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Samuel AjayiNephrology Unit, Department of Medicine, University College Hospital and College of Medicine, University of Ibadan, Ibadan, Nigeria.
Adewole AdebiyiCardiology Unit, Department of Medicine, University College Hospital and College of Medicine, University of Ibadan, Ibadan, Nigeria.
Solomon KadiriNephrology Unit, Department of Medicine, University College Hospital and College of Medicine, University of Ibadan, Ibadan, Nigeria.
University College Hospital, Ibadan · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUnderstanding the risk factors of hypertension has led to a better understanding of the pathogenesis, prevention and reduction in morbidity of hypertension. It is well known that offsprings of hypertensive parents have an increased risk of developing hypertension. It is therefore necessary to explore the physiological differences between normotensive patients with and without a positive family history of hypertension with respect to their urinary excretion of sodium.

methodsThis study was carried out at the University College Hospital, Ibadan Nigeria, to determine if normotensive patients with a positive family history of hypertension are different with respect to their urinary excretion of electrolytes and blood pressure. It examined the relationship between 24-hour urinary excretion of sodium, chloride and potassium, urea and creatinine and blood pressure in subjects with and without family history of hypertension. It was a case-control study of sixty-two subjects: normotensive patients' first degree relatives of primary hypertensive patients and normotensive patients without positive family history.

resultsThe mean (SD) systolic blood pressures for subjects with and without family history of hypertension were significantly different: 120.0(22.25) and 105.0(17.50) respectively, (p=0.001). The mean arterial blood pressures were significantly different: 86.4(10.2) mmHg and 80.1(8.1) mmHg respectively (p=0.010). The mean (SD) 24-hour urinary excretion of sodium for normotensive patients with and without positive family history of hypertension were 180.5 (45.50) mEq/L, and 156.0(36.25) mEq/L respectively. Systolic blood pressure and 24-hour urinary excretion of sodium was also higher in normotensive subjects with a positive family history of hypertension.

conclusionSystolic blood pressure and twenty-four hour urinary excretion of sodium were higher in normotensive subjects with a positive family history of hypertension than in those without a family history of hypertension.

Indexed as

Family HealthAdultBlood PressureBlood Pressure DeterminationCase-Control StudiesElectrolytesFemaleHumansHypertensionMaleMiddle AgedNigeriaRisk FactorsSodiumYoung AdultElectrolytesSodiumfirst degree relativesHypertensionurinars sodium excretion

Identifiers

PMID31086621
PMCPMC6488237
OpenAlexW2899622482

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.