ArticleThe Pan African medical journal2018
Irrational use of antibiotics in the Moshi Municipality Northern Tanzania: a cross sectional study.
Article in The Pan African medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.
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Who cites it
63 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- No prescription? No problem: drivers of non-prescribed sale of antibiotics among community drug retail outlets in low and middle income countries: a systematic review of qualitative studies.BMC public health · 2021Pooled it
- Non-prescription dispensing of antibiotic agents among community drug retail outlets in Sub-Saharan African countries: a systematic review and meta-analysis.Antimicrobial resistance and infection control · 2021Pooled it
- Health system and treatment regimen determinants of delayed first-dose antibiotic administration in hospitalized adults in Uganda.Research square · 2026Article
- A systematic review of antimicrobial stewardship practices and challenges in sub-Sahara Africa (SSA) regulated retail medicine settings.JAC-antimicrobial resistance · 2026Review
- A point prevalence survey on antibiotic dispensing practices identifies targets for quality improvement of antimicrobial stewardship in community pharmacies in Dar es Salaam, Tanzania.Journal of pharmaceutical policy and practice · 2026Article
- Formal and informal digital health in Tanzania: healthcare workforce, regulatory and trust implications of e-patients and virtual care and the development of the TRUST framework.Frontiers in health services · 2026Review
- Geospatial analysis of regional variations in antibiotic consumption in Tanzania from 2020 to 2024 using the electronic logistics management information system.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Status and implications of the knowledge, attitudes and practices towards AWaRe antibiotic use, resistance and stewardship among low- and middle-income countries.JAC-antimicrobial resistance · 2025Review
- Exploring the clinical value of procalcitonin, c-reactive protein, white blood cell count, and neutrophil-to-lymphocyte ratio in the early diagnosis of bloodstream infections in children.BMC pediatrics · 2025Article
- Exploring drivers of self-treatment with antibiotics in three agricultural communities of northern Tanzania.Antimicrobial resistance and infection control · 2024Article
- Inappropriate antibiotic access practices at the community level in Eastern Ethiopia.Scientific reports · 2024Article
- The Public Health Importance and Management of Infectious Poultry Diseases in Smallholder Systems in Africa.Foods (Basel, Switzerland) · 2024Review
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- A Narrative Review of Recent Antibiotic Prescribing Practices in Ambulatory Care in Tanzania: Findings and Implications.Medicina (Kaunas, Lithuania) · 2023Review
- PCT, IL-6, and IL-10 facilitate early diagnosis and pathogen classifications in bloodstream infection.Annals of clinical microbiology and antimicrobials · 2023Article
- Antibiotic Knowledge, Antibiotic Resistance Knowledge, and Antibiotic Use: A Cross-Sectional Study among Community Members of Bangkok in Thailand.Antibiotics (Basel, Switzerland) · 2023Article
- Antibacterial Utilization for Febrile Illnesses and Laboratory-Confirmed Bloodstream Infections in Northern Tanzania.Open forum infectious diseases · 2023Article
- Antimicrobial Resistance Patterns and Risk Factors Associated with ESBL-Producing and MDRMicroorganisms · 2023Article
- Combating Microbial Infections Using Metal-Based Nanoparticles as Potential Therapeutic Alternatives.Antibiotics (Basel, Switzerland) · 2023Review
3 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors.
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Abstract
introductionIrrational use of antibiotics includes prescription of incorrect doses, self-medication and treatment of non-bacterial illness. As a direct consequence of irrational antibiotic use, resistance to the commonly available antibiotics has been increasing rapidly. This phenomenon is associated with poorer health outcomes, longer hospitalization, increased cost to both the patient and government, and increased mortality. The aim of this study was to determine the prevalence of, and examine factors associated with, irrational use of antibiotics in the Moshi municipality, Northern Tanzania.
methodsWe conducted a cross-sectional descriptive study between April and May 2017 in the Moshi municipality. Twelve drug outlets, of which five were pharmacies and seven accredited drug dispensing outlets (ADDOs), were selected at random. On exiting these outlets, all adults who had purchased antibiotics were interviewed using structured questionnaires.
resultsA total of 152 adults were enrolled in this study. The median (QR) age was 31 years (25-42). The majority, 94 (61.8%), of the participants were female. ADDOs contributed 81 (53.3%) and pharmacies contributed 71 (46.7%) of all participants. Overall, 135 (88.8%) of antibiotic purchases were irrational. The most prevalent form of irrational antibiotic use was non-prescription usage; 116 of the 152 (76.3%) purchases fell in this category. Purchases of the incomplete dosage and purchases for non-bacterial illness were also widespread. Poor knowledge about the use of antibiotics had a significant association with irrational use of antibiotics (aOR=5.1, 95% CI: 1.80-15.15).
conclusionIrrational use of antibiotics is highly prevalent in this population. Non-prescription use of antibiotics is the most prevalent form. Poor knowledge about antibiotic use plays a significant role in irrational antibiotic use. There is a need to review the accessibility of antibiotics in drug outlets.
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